DpC

DpC Structure
DpC structure
Common Name DpC
CAS Number 1382469-39-7 Molecular Weight 353.48
Density 1.2±0.1 g/cm3 Boiling Point 510.7±48.0 °C at 760 mmHg
Molecular Formula C19H23N5S Melting Point N/A
MSDS USA Flash Point 262.7±29.6 °C
Symbol GHS06
GHS06
Signal Word Danger

The proto-oncogene c-Src and its downstream signaling pathways are inhibited by the metastasis suppressor, NDRG1.

Oncotarget 6 , 8851-74, (2015)

N-myc downstream regulated gene-1 (NDRG1) is a potent metastasis suppressor that plays a key role in regulating signaling pathways involved in mediating cancer cell invasion and migration, including those derived from prostate, colon, etc. However, the mechan...

The Metastasis Suppressor, N-MYC Downstream-regulated Gene-1 (NDRG1), Down-regulates the ErbB Family of Receptors to Inhibit Downstream Oncogenic Signaling Pathways.

J. Biol. Chem. 291 , 1029-52, (2016)

N-MYC downstream-regulated gene-1 (NDRG1) is a potent growth and metastasis suppressor that acts through its inhibitory effects on a wide variety of cellular signaling pathways, including the TGF-β pathway, protein kinase B (AKT)/PI3K pathway, RAS, etc. To in...