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8-喹啉磺酰氯

8-喹啉磺酰氯结构式
8-喹啉磺酰氯结构式
品牌特惠专场
常用名 8-喹啉磺酰氯 英文名 8-Quinolinesulfonyl chloride
CAS号 18704-37-5 分子量 227.667
密度 1.5±0.1 g/cm3 沸点 355.9±17.0 °C at 760 mmHg
分子式 C9H6ClNO2S 熔点 126-129 °C(lit.)
MSDS 中文版 美版 闪点 169.0±20.9 °C
符号 GHS05
GHS05
信号词 Danger

Carbonic anhydrase inhibitors: synthesis of water-soluble, topically effective intraocular pressure lowering aromatic/heterocyclic sulfonamides containing 8-quinoline-sulfonyl moieties: is the tail more important than the ring?

Bioorg. Med. Chem. 7(11) , 2397-406, (1999)

Reaction of 20 aromatic/heterocyclic sulfonamides containing a free amino, imino, hydrazino or hydroxyl group, with 8-quinoline-sulfonyl chloride afforded a series of water-soluble (as hydrochloride or triflate salts) compounds. The new derivatives were assay...

QSAR study on carbonic anhydrase inhibitors: aromatic/heterocyclic sulfonamides containing 8-quinoline-sulfonyl moieties, with topical activity as antiglaucoma agents.

Eur. J. Med. Chem. 39(7) , 593-600, (2004)

Quantitative structure-activity-relationship (QSAR) study on aromatic/heterocyclic sulfonamides containing 8-quinoline-sulfonyl carbonic anhydrase (CA) inhibitors has been carried out topologically using first-order valence connectivity index ((1)chi(v)). Exc...

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H. Takaku, M. Yoshida

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