8-Quinolinesulfonyl chloride

8-Quinolinesulfonyl chloride Structure
8-Quinolinesulfonyl chloride structure
Common Name 8-Quinolinesulfonyl chloride
CAS Number 18704-37-5 Molecular Weight 227.667
Density 1.5±0.1 g/cm3 Boiling Point 355.9±17.0 °C at 760 mmHg
Molecular Formula C9H6ClNO2S Melting Point 126-129 °C(lit.)
MSDS Chinese USA Flash Point 169.0±20.9 °C
Symbol GHS05
GHS05
Signal Word Danger

Carbonic anhydrase inhibitors: synthesis of water-soluble, topically effective intraocular pressure lowering aromatic/heterocyclic sulfonamides containing 8-quinoline-sulfonyl moieties: is the tail more important than the ring?

Bioorg. Med. Chem. 7(11) , 2397-406, (1999)

Reaction of 20 aromatic/heterocyclic sulfonamides containing a free amino, imino, hydrazino or hydroxyl group, with 8-quinoline-sulfonyl chloride afforded a series of water-soluble (as hydrochloride or triflate salts) compounds. The new derivatives were assay...

QSAR study on carbonic anhydrase inhibitors: aromatic/heterocyclic sulfonamides containing 8-quinoline-sulfonyl moieties, with topical activity as antiglaucoma agents.

Eur. J. Med. Chem. 39(7) , 593-600, (2004)

Quantitative structure-activity-relationship (QSAR) study on aromatic/heterocyclic sulfonamides containing 8-quinoline-sulfonyl carbonic anhydrase (CA) inhibitors has been carried out topologically using first-order valence connectivity index ((1)chi(v)). Exc...

H. Takaku et al.

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H. Takaku, M. Yoshida

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