![]() 马来酸美西麦角结构式
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常用名 | 马来酸美西麦角 | 英文名 | Methysergide |
---|---|---|---|---|
CAS号 | 129-49-7 | 分子量 | 469.53000 | |
密度 | 1.28g/cm3 | 沸点 | 634.4ºC at 760 mmHg | |
分子式 | C25H31N3O6 | 熔点 | N/A | |
MSDS | 中文版 美版 | 闪点 | 337.5ºC | |
符号 |
![]() GHS06 |
信号词 | Danger |
Pharmacological action of DA-9701 on the motility of feline stomach circular smooth muscle.
Pharmazie 70(3) , 183-92, (2015) DA-9701, a new prokinetic agent for the treatment of functional dyspepsia, is formulated with Pharbitis semen and Corydalis tuber. This study wasconducted to determine the pharmacological action of DA-9701 and to identify the receptors involved in DA-9701 -in... |
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Serotonin, but not dopamine, controls the stress response and anxiety-like behavior in the crayfish Procambarus clarkii.
J. Exp. Biol. 218 , 2745-52, (2015) In the animal kingdom, biogenic amines are widespread modulators of the nervous system that frequently interact to control mood. Our previous investigations in crayfish (Procambarus clarkii) have established that stress induces changes in brain serotonin (5-H... |
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Role of 5-HT1B/1Dreceptors in the reduction of formalin-induced nociception and secondary allodynia/hyperalgesia produced by antimigraine drugs in rats
Life Sci. 92(22) , 1046-54, (2013) Aims The present study analyzed the potential antinociceptive effect of the antimigraine drugs sumatriptan, dihydroergotamine or methysergide in rats submitted to the formalin test. Moreover, by using selective antagonists, the role of 5-HT1B/1D serotonergic ... |
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Antidepressant-like effect of the novel MAO inhibitor 2-(3,4-dimethoxy-phenyl)-4,5-dihydro-1H-imidazole (2-DMPI) in mice.
Prog. Neuropsychopharmacol. Biol. Psychiatry 39(1) , 31-9, (2012) Monoamine oxidase (MAO) inhibitors were the first antidepressant drugs to be prescribed and are still used today with great success, especially in patients resistant to other antidepressants. In this study, we evaluated the MAO inhibitory properties and the p... |
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Stimulation-Produced Analgesia From the Occipital or Retrosplenial Cortex of Rats Involves Serotonergic and Opioid Mechanisms in the Anterior Pretectal Nucleus
J. Pain 12(5) , 523-30, (2011) The electrical stimulation of the occipital (OC) or retrosplenial (RSC) cortex produces antinociception in the rat tail-flick test. These cortices send inputs to the anterior pretectal nucleus (APtN) which is implicated in antinociception and nociception. At ... |
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Neurotransmitter-mediated action of an antagonist of growth hormone-releasing hormone on anxiolysis in mice
Behav. Brain Res. 233(1) , 232-6, (2012) Highlights ► The involvement of transmitters in the anxiolytic action of GH-RH antagonist, MZ-4-71, has been tested in plus maze. ► In the experiments the animals were pretreated with phenoxybenzamine, prazosin, yohimbine, methysergide,cyproheptadine and bicu... |
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Antinociceptive effect of stimulating the zona incerta with glutamate in rats.
Pharmacol. Biochem. Behav. 101(3) , 360-8, (2012) The zona incerta (ZI) is a subthalamic nucleus connected to several structures, some of them known to be involved with antinociception. The ZI itself may be involved with both antinociception and nociception. The antinociceptive effects of stimulating the ZI ... |
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Stimulation of the occipital or retrosplenial cortex reduces incision pain in rats.
Pharmacol. Biochem. Behav. 100(2) , 220-7, (2011) The electrical stimulation of the occipital (OC) or retrosplenial (RSC) cortex produces antinociception in the rat tail-flick and formalin tests. This study examined the antinociceptive effects of stimulating the OC or RSC in a rat model of post-incision pain... |
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What happens to the old headache medicines?
Headache 52(4) , 701-6, (2012) Old headache medicines never die; they either fade away or come back in disguise. The disguise is often a new route of administration, which may work better, faster, more completely, with fewer adverse events, and/or have certain other advantages. The clinica... |
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Latent inhibition in an insect: the role of aminergic signaling.
Learn. Mem. 19(12) , 593-7, (2012) Latent inhibition (LI) is a decrement in learning performance that results from the nonreinforced pre-exposure of the to-be-conditioned stimulus, in both vertebrates and invertebrates. In vertebrates, LI development involves dopamine and serotonin; in inverte... |