Methysergide
Methysergide structure
|
Common Name | Methysergide | ||
|---|---|---|---|---|
| CAS Number | 129-49-7 | Molecular Weight | 469.53000 | |
| Density | 1.28g/cm3 | Boiling Point | 634.4ºC at 760 mmHg | |
| Molecular Formula | C25H31N3O6 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 337.5ºC | |
| Symbol |
GHS06 |
Signal Word | Danger | |
Use of MethysergideMethysergide is a prescription drug formerly used for prophylaxis of cluster headaches/migraine headaches, but is no longer recommended due to retroperitoneal/retropulmonary fibrosis. It is also used in carcinoid syndrome to treat severe diarrhea. It may also be used in the treatment of serotonin syndrome. |
| Name | Methysergide maleate salt |
|---|---|
| Synonym | More Synonyms |
| Density | 1.28g/cm3 |
|---|---|
| Boiling Point | 634.4ºC at 760 mmHg |
| Molecular Formula | C25H31N3O6 |
| Molecular Weight | 469.53000 |
| Flash Point | 337.5ºC |
| Exact Mass | 469.22100 |
| PSA | 132.10000 |
| LogP | 1.97570 |
| Vapour Pressure | 5.74E-17mmHg at 25°C |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
MUTATION DATA
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| Symbol |
GHS06 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H301 |
| Precautionary Statements | Missing Phrase - N15.00950417 |
| Personal Protective Equipment | Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges |
| Hazard Codes | T: Toxic; |
| Risk Phrases | R25 |
| Safety Phrases | S45 |
| RIDADR | UN 2811 6 |
| WGK Germany | 3 |
| RTECS | KE5410000 |
| Packaging Group | III |
| Hazard Class | 6.1(b) |
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Pharmacological action of DA-9701 on the motility of feline stomach circular smooth muscle.
Pharmazie 70(3) , 183-92, (2015) DA-9701, a new prokinetic agent for the treatment of functional dyspepsia, is formulated with Pharbitis semen and Corydalis tuber. This study wasconducted to determine the pharmacological action of DA... |
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Serotonin, but not dopamine, controls the stress response and anxiety-like behavior in the crayfish Procambarus clarkii.
J. Exp. Biol. 218 , 2745-52, (2015) In the animal kingdom, biogenic amines are widespread modulators of the nervous system that frequently interact to control mood. Our previous investigations in crayfish (Procambarus clarkii) have esta... |
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Role of 5-HT1B/1Dreceptors in the reduction of formalin-induced nociception and secondary allodynia/hyperalgesia produced by antimigraine drugs in rats
Life Sci. 92(22) , 1046-54, (2013) Aims The present study analyzed the potential antinociceptive effect of the antimigraine drugs sumatriptan, dihydroergotamine or methysergide in rats submitted to the formalin test. Moreover, by using... |
| Methysergide maleate |
| Methysergide maleate,[8β(S)]-9,10-Didehydro-N-[1-(hydroxymethyl)propyl]-1,6-dimethylergoline-8-carboxamidemaleate |
| MFCD00083185 |
| EINECS 204-950-9 |