鸟苷5'-O-(2-硫代二磷酸)三锂盐
鸟苷5'-O-(2-硫代二磷酸)三锂盐结构式
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常用名 | 鸟苷5'-O-(2-硫代二磷酸)三锂盐 | 英文名 | Guanosine 5′-[β-thio]diphosphate trilithium salt |
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| CAS号 | 97952-36-8 | 分子量 | 477.06500 | |
| 密度 | N/A | 沸点 | N/A | |
| 分子式 | C10H12Li3N5O10P2S | 熔点 | 230 °C (dec.) | |
| MSDS | 美版 | 闪点 | N/A | |
| 符号 |
GHS07 |
信号词 | Warning |
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A potentially novel nicotinic receptor in Aplysia neuroendocrine cells.
J. Neurophysiol. 112(2) , 446-62, (2014) Nicotinic receptors form a diverse group of ligand-gated ionotropic receptors with roles in both synaptic transmission and the control of excitability. In the bag cell neurons of Aplysia, acetylcholine activates an ionotropic receptor, which passes inward cur... |
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Role for protein kinase C in controlling Aplysia bag cell neuron excitability.
Neuroscience 179 , 41-55, (2011) Targeting signalling molecules to ion channels can expedite regulation and assure the proper transition of changes to excitability. In the bag cell neurons of Aplysia, single-channel studies of excised patches have revealed that protein kinase C (PKC) gates a... |
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Conditional inhibition of forskolin-activated adenylate cyclase by guanosine diphosphate and its analog.
Arch. Biochem. Biophys. 251 , 148-155, (1986) Forskolin-activated adenylate cyclases (AC) in intact membranes, solubilized with Lubrol or eluted following adsorption on a forskolin-Sepharose column, were examined for inhibition by GDP and GDP beta S. AC in intact membranes of rat or rabbit adipocytes was... |
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GDP beta S enhances the activation of phospholipase C caused by thrombin in human platelets: evidence for involvement of an inhibitory GTP-binding protein.
Biochem. Biophys. Res. Commun. 144 , 1188-1196, (1987) Guanosine 5'-O-thiotriphosphate (GTP gamma S) and thrombin stimulate the activity of phospholipase C in platelets that have been permeabilized with saponin and whose inositol phospholipids have been prelabeled with [3H]inositol. Ca2+ has opposite effects on t... |
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Inhibition of GDP beta S of agonist-activated phospholipase C in human platelets requires cell permeabilization.
Biochem. Biophys. Res. Commun. 153 , 417-421, (1988) The inhibition by guanosine 5'-[beta-thio]diphosphate (GDP beta S) of phospholipase C was compared in intact and saponin-permeabilized human platelets in order to assess whether effects of GDP beta S on phospholipase C activation unrelated to guanine nucleoti... |
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Gi-protein inhibitor, guanosine 5′-O-(2-thiodiphosphate), induces senescence-associated β-galactosidase positive cell formation through CREB phosphorylation
Leuk. Res. 86 , 683-90, (2010) Aims We evaluated Gi-protein inhibitor, guanosine 5′-O-(2-thiodiphosphate)(GOT)-induced senescence-associated(SA)-β-galactosidase(Gal) positive cell formation to determine if it occurred through phosphorylation of cyclic AMP-dependent response element binding... |