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2,2,2-三氟乙基磺酰氯

2,2,2-三氟乙基磺酰氯结构式
2,2,2-三氟乙基磺酰氯结构式
品牌特惠专场
常用名 2,2,2-三氟乙基磺酰氯 英文名 2,2,2-Trifluoroethanesulfonyl chloride
CAS号 1648-99-3 分子量 182.549
密度 1.7±0.1 g/cm3 沸点 147.5±0.0 °C at 760 mmHg
分子式 C2H2ClF3O2S 熔点 N/A
MSDS 中文版 美版 闪点 72.2±0.0 °C
符号 GHS05
GHS05
信号词 Danger

Tresyl-based conjugation of protein antigen to lipid nanoparticles increases antigen immunogenicity

Int. J. Pharm. 401(1-2) , 87-92, (2010)

The present studies were aimed at investigating the engineering of NPs with protein-conjugated-surfactant at their surface. In order to increase the immunogenicity of a protein antigen, Brij 78 was functionalized by tresyl chloride and then further reacted wi...

Compared stability of Sepharose-based immunoadsorbents prepared by various activation methods.

J. Chromatogr. A. 584(1) , 17-22, (1992)

During the use of chromatographic supports for the purification of proteins or the selective removal of substances by immunoaffinity, leakage of the antibodies immobilized on the matrix is systematically observed. When the cleansing of blood plasma by extraco...

Multifunctional commercially pure titanium for the improvement of bone integration: Multiscale topography, wettability, corrosion resistance and biological functionalization.

Mater. Sci. Eng. C. Mater. Biol. Appl. 60 , 384-93, (2015)

The objects of this research are commercially pure titanium surfaces, with multifunctional behavior, obtained through a chemical treatment and biological functionalization. The explored surfaces are of interest for dental implants, in contact with bone, where...

Tresyl-mediated synthesis: kinetics of competing coupling and hydrolysis reactions as a function of pH, temperature, and steric factors.

Bioconjug. Chem. 10(2) , 213-20, (1999)

Kinetic parameters have been measured for coupled nucleophilic and solvolytic reactions of 2,2,2-trifluoroethanesulfonyl (tresyl)-modified poly(ethylene glycol) based on a system of coupled differential equations implied by recently proposed elementary reacti...

Receptor-specific targeting with liposomes in vitro based on sterol-PEG(1300) anchors.

Pharm. Res. 26(3) , 529-38, (2009)

The challenge in developing liposomes to be used in active drug targeting is to design a method that can be used for modifying liposomal membranes that is applicable for a number of different specific ligands. In this study, the post insertion technique was u...

Simple-kinetic descriptions of alcohol dehydrogenase after immobilization on tresyl-chloride-activated agarose.

Eur. J. Biochem. 160(2) , 343-8, (1986)

Yeast alcohol dehydrogenase was successfully immobilized on tresyl-chloride-activated agarose; the optimized conditions allowed an enzyme activity recovery of over 90%. Comparison of free and immobilized enzyme properties showed an unchanged intrinsic activat...

Direct attachment of fibronectin to tresyl chloride-activated titanium.

J. Biomed. Mater. Res. A 67(2) , 684-8, (2003)

The aim of this study was to bind fibronectin directly to a titanium surface treated with tresyl chloride (2,2,2-trifluoroethanesulfonyl chloride) for the development of a strong connection of a dental implant to subepithelial connective tissues and/or peri-i...

Coupling of poly(ethylene glycol) to albumin under very mild conditions by activation with tresyl chloride: characterization of the conjugate by partitioning in aqueous two-phase systems.

Biotechnol. Appl. Biochem. 12 , 119, (1990)

Poly(ethylene glycol) activated with tresyl chloride has been covalently linked to albumin as a result of a 2-h incubation in 0.05 M sodium phosphate buffer, pH 7.5, containing 0.125 M sodium chloride (0.344 OSM). The coupling of poly(ethylene glycol) to albu...

Quartz-crystal microbalance-dissipation technique for the study of initial adsorption of fibronectin onto tresyl chloride-activated titanium.

J. Biomed. Mater. Res. B. Appl. Biomater. 73(2) , 271-6, (2005)

The immobilization of cell-adhesive proteins onto titanium implants improves biological response at the implant-tissue interface. Previous studies demonstrated the easy and direct attachment of fibronectin onto titanium with the use of a 2,2,2-trifluoroethane...

Tresyl activation of a hydroxyalkyl ligand for coupling to a hydrazide gel: stable immobilization of T-2 toxin for affinity purification of T-2 antibody.

Anal. Biochem. 162(1) , 171-7, (1987)

A stable T-2 hydrazide gel is prepared by activating T-2 toxin with tresyl chloride followed by coupling to agarose-adipic acid hydrazide. Utilized as an affinity chromatography column, this T-2 hydrazide gel purifies a monoclonal antibody for T-2 in high yie...