BuChE-IN-5

Modify Date: 2023-03-11 09:06:28

BuChE-IN-5 structure	Common Name	BuChE-IN-5
	CAS Number	2402753-39-1	Molecular Weight	377.57
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₅H₃₅N₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of BuChE-IN-5

BuChE-IN-5 (compound 25b) is a potent BuChE inhibitor with an IC50 value of 1.94 μM. BuChE-IN-5 efficiently inhibits aggregation Aβ and tau protein in Escherichia coli. BuChE-IN-5 also has free radical scavenging capacity and antioxidant activity. BuChE-IN-5 can be used for researching Alzheimer’s disease[1].

Name	BuChE-IN-5

Description	BuChE-IN-5 (compound 25b) is a potent BuChE inhibitor with an IC50 value of 1.94 μM. BuChE-IN-5 efficiently inhibits aggregation Aβ and tau protein in Escherichia coli. BuChE-IN-5 also has free radical scavenging capacity and antioxidant activity. BuChE-IN-5 can be used for researching Alzheimer’s disease[1].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> AChE
Target	Butyrylcholinesterase:1.94 μM (IC50)
References	[1]. Wichur T, et al. 1-Benzylpyrrolidine-3-amine-based BuChE inhibitors with anti-aggregating, antioxidant and metal-chelating properties as multifunctional agents against Alzheimer's disease. Eur J Med Chem. 2020 Feb 1;187:111916.

Molecular Formula	C₂₅H₃₅N₃
Molecular Weight	377.57

BuChE-IN-5

Use of BuChE-IN-5

Names

BuChE-IN-5 Biological Activity

Chemical & Physical Properties