2669070-40-8

2669070-40-8 structure

Name: BuChE-IN-1
Chemical Name: BuChE-IN-1
CAS Number: 2669070-40-8
Molecular Formula: C₂₃H₂₃FN₂O₄S
Molecular Weight: 442.50
Create Date: 2022-05-19 17:49:04
Modify Date: 2025-08-27 14:14:32
BuChE-IN-1 (Compound 23) is a potent inhibitor of butyrylcholinesterase (BuChE). Butyrylcholinesterase (BuChE) is recently regarded as a biomarker in progressed Alzheimer’s disease (AD). BuChE-IN-1 shows low cytotoxicity and high blood brain barrier (BBB) permeability. BuChE-IN-1 is a promising BuChE inhibitor for the research of AD[1].

Name	BuChE-IN-1

Description	BuChE-IN-1 (Compound 23) is a potent inhibitor of butyrylcholinesterase (BuChE). Butyrylcholinesterase (BuChE) is recently regarded as a biomarker in progressed Alzheimer’s disease (AD). BuChE-IN-1 shows low cytotoxicity and high blood brain barrier (BBB) permeability. BuChE-IN-1 is a promising BuChE inhibitor for the research of AD[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
References	[1]. MeiyangXi, et al. Design, synthesis, biological evaluation and molecular modeling of N-isobutyl-N-((2-(p-tolyloxymethyl)thiazol-4yl)methyl)benzo[d][1,3] dioxole-5-carboxamides as selective butyrylcholinesterase inhibitors.

Molecular Formula	C₂₃H₂₃FN₂O₄S
Molecular Weight	442.50