2003213-07-6

2003213-07-6 structure

Name: BuChE-IN-6
Chemical Name: BuChE-IN-6
CAS Number: 2003213-07-6
Molecular Formula: C₂₁H₂₆N₄O₂
Molecular Weight: 366.46
Catalog: Signaling Pathways Neuronal Signaling AChE
Create Date: 2022-08-14 12:55:11
Modify Date: 2024-01-29 17:19:38
BuChE-IN-6 (compound 1b) is a potent and selective BuChE (butyrylcholinesterase) inhibitor, with IC50 values of 0.46 and 0.51 μM for eqBuChE and hBuChE, respectively. BuChE-IN-6 also inhibits Aβ42 self-aggregation[1].

Name	BuChE-IN-6

Description	BuChE-IN-6 (compound 1b) is a potent and selective BuChE (butyrylcholinesterase) inhibitor, with IC50 values of 0.46 and 0.51 μM for eqBuChE and hBuChE, respectively. BuChE-IN-6 also inhibits Aβ42 self-aggregation[1].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> AChE
Target	Butyrylcholinesterase:0.46 μM (IC50, eqBuChE) Butyrylcholinesterase:0.51 μM (IC50, hBuChE)
References	[1]. Marques CS, et al. N-1,2,3-triazole-isatin derivatives for cholinesterase and β-amyloid aggregation inhibition: A comprehensive bioassay study. Bioorg Chem. 2020 May;98:103753.

Molecular Formula	C₂₁H₂₆N₄O₂
Molecular Weight	366.46