2'-Deoxycytidine monohydrate

Modify Date: 2024-01-02 14:51:10

2'-Deoxycytidine monohydrate Structure
2'-Deoxycytidine monohydrate structure
Common Name 2'-Deoxycytidine monohydrate
CAS Number 951-77-9 Molecular Weight 227.22
Density 1.7±0.1 g/cm3 Boiling Point 482.1±55.0 °C at 760 mmHg
Molecular Formula C9H13N3O4 Melting Point 209-211 °C(lit.)
MSDS USA Flash Point 245.4±31.5 °C

 Use of 2'-Deoxycytidine monohydrate


2'-Deoxycytidine, a deoxyribonucleoside, could inhibit biological effects of Bromodeoxyuridine (Brdu).

 Names

Name 2'-deoxycytidine
Synonym More Synonyms

 2'-Deoxycytidine monohydrate Biological Activity

Description 2'-Deoxycytidine, a deoxyribonucleoside, could inhibit biological effects of Bromodeoxyuridine (Brdu).
Related Catalog
Target

Human Endogenous Metabolite

Brdu

References

[1]. Horn D, et al. Inhibition of biological effects of bromodeoxyuridine by deoxycytidine: correlation with decreased incorporation of bromodeoxyuridine into DNA. Somatic Cell Genet. 1976 Sep;2(5):469-81.

 Chemical & Physical Properties

Density 1.7±0.1 g/cm3
Boiling Point 482.1±55.0 °C at 760 mmHg
Melting Point 209-211 °C(lit.)
Molecular Formula C9H13N3O4
Molecular Weight 227.22
Flash Point 245.4±31.5 °C
PSA 119.83000
LogP -1.73
Vapour Pressure 0.0±2.7 mmHg at 25°C
Index of Refraction 1.720
Storage condition Store at RT.
Water Solubility H2O: 50 mg/mL, clear, colorless

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
HA3800000
CHEMICAL NAME :
Cytidine, 2'-deoxy-
CAS REGISTRY NUMBER :
951-77-9
BEILSTEIN REFERENCE NO. :
0087567
LAST UPDATED :
199701
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C9-H13-N3-O4
MOLECULAR WEIGHT :
227.25
WISWESSER LINE NOTATION :
T6NVNJ DZ A- ET5OTJ B1Q CQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
DOSE :
800 mg/kg
SEX/DURATION :
female 9 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)

MUTATION DATA

TYPE OF TEST :
DNA inhibition
TEST SYSTEM :
Rodent - hamster Lung
DOSE/DURATION :
1 mmol/L
REFERENCE :
BICMBE Biochimie. (SPPIF, B.P.22, F-41353 Vineuil, France) V.53- 1971- Volume(issue)/page/year: 64,809,1982

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi
Safety Phrases S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS HA3800000

 Articles168

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 Synonyms

1-(2-Deoxy-β-D-ribofuranosyl)cytosine
EINECS 213-454-1
4-Amino-1-(2-deoxy-β-D-erythro-pentofuranosyl)-2(1H)-pyrimidinone
4-Amino-1-(2-deoxy-β-D-glycero-pentofuranosyl)pyrimidin-2(1H)-one
2-pyrimidinol, 1-(2-deoxy-β-D-erythro-pentofuranosyl)-1,4-dihydro-4-imino-
Cytidine, 2'-deoxy-
1-(2-Deoxy-β-D-erythro-pentofuranosyl)-4-imino-1,4-dihydro-2-pyrimidinol
1-(2-Deoxy-b-D-ribofuranosyl)cytosine
deoxycytidine
2'-Deoxycytidine monohydrate
4-Amino-1-(2-deoxy-b-D-erythro-pentofuranosyl)-2(1H)-pyrimidinone
2(1H)-pyrimidinone, 4-amino-1-(2-deoxy-β-D-glycero-pentofuranosyl)-
2‘-Deoxycytidine
1-(2-deoxy-β-D-erythro-pentofuranosyl)-Cytosine
MFCD00006547
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