5'-O-Dimethoxytrityl-N-benzoyl-desoxycytidine

Modify Date: 2025-08-27 10:44:27

5'-O-Dimethoxytrityl-N-benzoyl-desoxycytidine structure	Common Name	5'-O-Dimethoxytrityl-N-benzoyl-desoxycytidine
	CAS Number	67219-55-0	Molecular Weight	633.69000
	Density	1.27 g/cm3	Boiling Point	N/A
	Molecular Formula	C₃₇H₃₅N₃O₇	Melting Point	119 °C
	MSDS	Chinese USA	Flash Point	N/A
	Symbol	GHS08	Signal Word	Danger

Use of 5'-O-Dimethoxytrityl-N-benzoyl-desoxycytidine

N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine (5'-O-DMT-N4-Bz-dC) can be used for synthesis oligodeoxynucleotides containing a 3'-S-phosphorothiolate (3'-PS) linkage. N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine is an useful tool for probing enzyme-catalyzed cleavage processes in DNA[1].

Name	N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine
Synonym	More Synonyms

Description	N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine (5'-O-DMT-N4-Bz-dC) can be used for synthesis oligodeoxynucleotides containing a 3'-S-phosphorothiolate (3'-PS) linkage. N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine is an useful tool for probing enzyme-catalyzed cleavage processes in DNA[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. James W Gaynor, et al. Synthesis of the 3'-thio-nucleosides and subsequent automated synthesis of oligodeoxynucleotides containing a 3'-S-phosphorothiolate linkage. Nat Protoc. 2007;2(12):3122-35.

Density	1.27 g/cm3
Melting Point	119 °C
Molecular Formula	C₃₇H₃₅N₃O₇
Molecular Weight	633.69000
Exact Mass	633.24800
PSA	121.14000
LogP	5.24290
Index of Refraction	58 ° (C=1, MeOH)
InChIKey	MYSNCIZBPUPZMQ-VOTWKOMSSA-N
SMILES	COc1ccc(C(OCC2OC(n3ccc(NC(=O)c4ccccc4)nc3=O)CC2O)(c2ccccc2)c2ccc(OC)cc2)cc1
Storage condition	−20°C

MSDS(Chinese)

Symbol	GHS08
Signal Word	Danger
Hazard Statements	H340-H350
Precautionary Statements	P201-P280-P308 + P313
Personal Protective Equipment	Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes	Xn: Harmful;
Risk Phrases	R40
Safety Phrases	S36/37
RIDADR	NONH for all modes of transport
WGK Germany	1

Precursor 8
CAS#:40615-36-9 4,4'-Dimethoxyt... CAS#:4836-13-9 N4-Benzoyl-2'-d... CAS#:951-77-9 2'-Deoxycytidin... CAS#:118352-74-2 5'-O-(4,4'-dime...
CAS#:98-88-4 Benzoyl chloride CAS#:3992-42-5 2'-Deoxycytidin... CAS#:65-85-0 benzoic acid CAS#:31501-22-1 N,3'-O,5'-O-Tri...
DownStream 5
CAS#:4836-13-9 N4-Benzoyl-2'-d... CAS#:74405-44-0 5'-O-(4,4'-DIME... CAS#:76512-82-8 5'-O-(4,4'-DIME... CAS#:807369-63-7 N4-(3-aminoprop...
CAS#:6220-63-9 2'-DEOXYCYTIDIN...

Diels-Alder cycloadditions in water for the straightforward preparation of peptide-oligonucleotide conjugates.

Nucleic Acids Res. 34(3) , e24, (2006)

The Diels-Alder reaction between diene-modified oligonucleotides and maleimide-derivatized peptides afforded peptide-oligonucleotide conjugates with high purity and yield. Synthesis of the reagents wa...

Aldrichimica Acta 20 , 52, (1987)

N-[1-[(2R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxyoxolan-2-yl]-2-oxopyrimidin-4-yl]benzamide

EINECS 266-605-9

MFCD00010114

5'-O-Dimethoxytrityl-N-benzoyl-desoxycytidine