Thrombin inhibitor 1 structure
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Common Name | Thrombin inhibitor 1 | ||
|---|---|---|---|---|
| CAS Number | 855998-46-8 | Molecular Weight | 497.32 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C22H20Cl2F2N4O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Thrombin inhibitor 1Thrombin inhibitor 1 is a potent thrombin inhibitor (Ki=0.66 nM, 2xaPTT=0.43 μM). |
| Name | Thrombin inhibitor 1 |
|---|
| Description | Thrombin inhibitor 1 is a potent thrombin inhibitor (Ki=0.66 nM, 2xaPTT=0.43 μM). |
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| Related Catalog | |
| Target |
Ki: 0.66 nM (thrombin)[1] |
| In Vitro | Thrombin inhibitor 1 (Compound 4) is binds in the active site of thrombin with Ki of 0.66 nM, 2xaPTT=0.43 uM). Thrombin inhibitor 1 (Compound 4) is evaluated for its thrombin inhibitory potency and its functional ability to double the activated partial thromboplastin time (2xaPTT) in human plasma with a 2xaPTT of 0.43 μM[1]. |
| References |
| Molecular Formula | C22H20Cl2F2N4O3 |
|---|---|
| Molecular Weight | 497.32 |
| InChIKey | QNBCEVFVDCKHNZ-UHFFFAOYSA-N |
| SMILES | CC(NC(=O)Cc1c(Cl)ccc(=NCC(F)(F)c2cccc[n+]2[O-])n1O)c1cccc(Cl)c1 |