Cyclophilin inhibitor 1

Modify Date: 2024-01-09 12:24:47

Cyclophilin inhibitor 1 structure	Common Name	Cyclophilin inhibitor 1
	CAS Number	1509904-96-4	Molecular Weight	593.67
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₁H₃₉N₅O₇	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Cyclophilin inhibitor 1

Cyclophilin inhibitor 1 is a potent and orally bioavailable cyclophilin A inhibitor, with a Kd of 5 nM, shows effective anti-HCV activity, with an EC50 of 98 nM for HCV 2a[1].

Name	Cyclophilin inhibitor 1

Description	Cyclophilin inhibitor 1 is a potent and orally bioavailable cyclophilin A inhibitor, with a Kd of 5 nM, shows effective anti-HCV activity, with an EC50 of 98 nM for HCV 2a[1].
Related Catalog	Signaling Pathways >> Anti-infection >> HCV Research Areas >> Infection
Target	Kd: 5 nM (Cyclophilin A)[1] EC50: 98 nM (HCV 2a)[1]
In Vitro	Cyclophilin inhibitor 1 (Compound 3) inhibits HCV 2a activity, with an EC50 of 98 nM[1].
References	[1]. Mackman RL, et al. Discovery of a Potent and Orally Bioavailable Cyclophilin Inhibitor Derived from the Sanglifehrin Macrocycle. J Med Chem. 2018 Nov 8;61(21):9473-9499.

Molecular Formula	C₃₁H₃₉N₅O₇
Molecular Weight	593.67