PTP inhibitor 1

Modify Date: 2025-08-22 16:26:15

PTP inhibitor 1 Structure
PTP inhibitor 1 structure
 Common Name PTP inhibitor 1
CAS Number 2632-13-5 Molecular Weight 229.071
Density 1.4±0.1 g/cm3 Boiling Point 306.7±17.0 °C at 760 mmHg
Molecular Formula C9H9BrO2 Melting Point 69-71 °C(lit.)
MSDS Chinese USA Flash Point 139.3±20.9 °C
Symbol GHS05 GHS07
GHS05, GHS07		 Signal Word Danger

 Use of PTP inhibitor 1


PTP inhibitor 1 is a protein tyrosine phosphatase (PTP) inhibitor, with anti-angiogenic effect[1].

 Names

Name 2-bromo-1-(4-methoxyphenyl)ethanone
Synonym More Synonyms

 PTP inhibitor 1 Biological Activity

Description PTP inhibitor 1 is a protein tyrosine phosphatase (PTP) inhibitor, with anti-angiogenic effect[1].
Related Catalog
Target

PTP[1]

In Vitro PTP inhibitor 1 exhibits anti-angiogenic activity with an IC50 of 3.7 μM for HUVECs[1].
References

[1]. Sylvest L, et al. Phosphatase inhibitors with anti-angiogenic effect in vitro. APMIS. 2010 Jan;118(1):49-59.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 306.7±17.0 °C at 760 mmHg
Melting Point 69-71 °C(lit.)
Molecular Formula C9H9BrO2
Molecular Weight 229.071
Flash Point 139.3±20.9 °C
Exact Mass 227.978592
PSA 26.30000
LogP 2.27
Vapour Pressure 0.0±0.6 mmHg at 25°C
Index of Refraction 1.554
Storage condition 2-8°C

 Safety Information

Symbol GHS05 GHS07
GHS05, GHS07
Signal Word Danger
Hazard Statements H314-H335
Precautionary Statements P261-P280-P305 + P351 + P338-P310
Personal Protective Equipment Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes Xi:Irritant
Risk Phrases R36/37/38
Safety Phrases S26-S27-S28-S36/37/39-S45-S37/39
RIDADR UN 3261 8/PG 2
WGK Germany 3
Packaging Group III
Hazard Class 8
HS Code 29147090

 Synthetic Route

 Customs

HS Code 2914700090
Summary HS: 2914700090 halogenated, sulphonated, nitrated or nitrosated derivatives of ketones and quinones, whether or not with other oxygen function Tax rebate rate:9.0% Supervision conditions:none VAT:17.0% MFN tariff:5.5% General tariff:30.0%

 Articles3

More Articles
Switching reversibility to irreversibility in glycogen synthase kinase 3 inhibitors: clues for specific design of new compounds.

J. Med. Chem. 54 , 4042-56, (2011)

Development of kinase-targeted therapies for central nervous system (CNS) diseases is a great challenge. Glycogen synthase kinase 3 (GSK-3) offers a great potential for severe CNS unmet diseases, bein...

QSAR study and conformational analysis of 4-arylthiazolylhydrazones derived from 1-indanones with anti-Trypanosoma cruzi activity.

Eur. J. Pharm. Sci. 78 , 190-7, (2015)

A set of 4-arylthiazolylhydrazones derived from 1-indanones (TZHs) previously synthesized and assayed against Trypanosoma cruzi, the causative agent of Chagas disease, were explored in terms of confor...

Synthesis of diblock copolymers bearing p-methoxyphenacyl side groups.

Polym. Chem. 2(10) , 2284-2292, (2011)

 Synonyms

α-Bromo-4'-methoxyacetophenone
p-methoxyphenacyl bromide
4'-Methoxyphenacyl Bromide
4-Methoxyphenacyl Br
ω-Bromo-4-methoxyacetophenone
2-Bromo-1-(4-methoxyphenyl)ethanone
4-Methoxyphenacyl bromide
2-Bromo-4′-methoxyacetophenone
2-Bromo-4‘-methoxyacetophenone
Acetophenone, 2-bromo-4'-methoxy-
2-Bromo-4'-methoxyacetophenone
MFCD00465443
2-bromo-1-(4'-methoxy-phenyl)-ethanone
2-Bromo-4'-methoxyacetophenone, Pract.
Ethanone,2-bromo-1-(4-methoxyphenyl)
1-(4-methoxyphenyl)-2-bromo-ethan-1-one
Ethanone, 2-bromo-1-(4-methoxyphenyl)-
EINECS 220-118-8
4-(Bromoacetyl)anisole
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