mTOR Inhibitor 1

Modify Date: 2025-08-27 11:00:45

mTOR Inhibitor 1 Structure
mTOR Inhibitor 1 structure
Common Name mTOR Inhibitor 1
CAS Number 2219323-96-1 Molecular Weight 411.46
Density N/A Boiling Point N/A
Molecular Formula C23H21N7O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of mTOR Inhibitor 1


mTOR Inhibitor 1 is a highlt potent, selective and oral mTOR inhibitor with an IC50 of 7 nM. mTOR Inhibitor 1 inhibits cellular phosphorylation of mTORC1 (pS6 and p4E-BP1) and mTORC2 (pAKT (S473)) substrates[1].

 Names

Name mTOR Inhibitor 1

 mTOR Inhibitor 1 Biological Activity

Description mTOR Inhibitor 1 is a highlt potent, selective and oral mTOR inhibitor with an IC50 of 7 nM. mTOR Inhibitor 1 inhibits cellular phosphorylation of mTORC1 (pS6 and p4E-BP1) and mTORC2 (pAKT (S473)) substrates[1].
Related Catalog
Target

mTOR:7 nM (IC50)

References

[1]. Guo Q, et al. Highly Selective, Potent, and Oral mTOR Inhibitor for Treatment of Cancer as Autophagy Inducer. J Med Chem. 2018 Feb 8;61(3):881-904.

 Chemical & Physical Properties

Molecular Formula C23H21N7O
Molecular Weight 411.46
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