sEH inhibitor-1

Modify Date: 2024-01-12 20:38:41

sEH inhibitor-1 structure	Common Name	sEH inhibitor-1
	CAS Number	1208549-68-1	Molecular Weight	371.354
	Density	1.4±0.1 g/cm3	Boiling Point	470.8±45.0 °C at 760 mmHg
	Molecular Formula	C₁₇H₂₀F₃N₃O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	238.5±28.7 °C

Use of sEH inhibitor-1

sEH inhibitor-1 (compound TCPU ) is a potent and oral active inhibitor of sEH (soluble epoxide hydrolase) with IC50s of 0.4 and 5.3 nM in human and murine, respectively[1].

Name	1-(1-(cyclopropanecarbonyl)piperidin-4-yl)-3-(4-(trifluoromethoxy)phenyl)urea
Synonym	More Synonyms

Description	sEH inhibitor-1 (compound TCPU ) is a potent and oral active inhibitor of sEH (soluble epoxide hydrolase) with IC50s of 0.4 and 5.3 nM in human and murine, respectively[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
Target	sEH[1]
References	[1]. Liu JY, et al. Substituted phenyl groups improve the pharmacokinetic profile and anti-inflammatory effect of urea-based soluble epoxide hydrolase inhibitors in murine models. Eur J Pharm Sci. 2013;48(4-5):619-627.

Density	1.4±0.1 g/cm3
Boiling Point	470.8±45.0 °C at 760 mmHg
Molecular Formula	C₁₇H₂₀F₃N₃O₃
Molecular Weight	371.354
Flash Point	238.5±28.7 °C
Exact Mass	371.145691
PSA	70.67000
LogP	2.15
Vapour Pressure	0.0±1.2 mmHg at 25°C
Index of Refraction	1.556

Urea, N-[1-(cyclopropylcarbonyl)-4-piperidinyl]-N'-[4-(trifluoromethoxy)phenyl]-

1-[1-(Cyclopropylcarbonyl)-4-piperidinyl]-3-[4-(trifluoromethoxy)phenyl]urea

DC Chemicals Limited
China
Product Name: sEH inhibitor-1
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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