340221-20-7

340221-20-7 structure

Name: sEH inhibitor-7
Chemical Name: way-353603
CAS Number: 340221-20-7
Molecular Formula: C₁₅H₂₁NO₂
Molecular Weight: 247.33
Catalog: Research Areas Inflammation/Immunology
Create Date: 2022-08-18 20:07:28
Modify Date: 2024-04-06 15:48:47
sEH inhibitor-7 (compound c-2) is an inhibitor of soluble epoxide hydrolase (sEH) with IC50s of 0.15 μM (mouse sEH) and 6.2 μM (human sEH), respectively. soluble epoxide hydrolase (sEH) plays an important role in the metabolism of endogenous chemical mediators involved in the regulation of blood pressure and inflammation[1].

Name	way-353603

Description	sEH inhibitor-7 (compound c-2) is an inhibitor of soluble epoxide hydrolase (sEH) with IC50s of 0.15 μM (mouse sEH) and 6.2 μM (human sEH), respectively. soluble epoxide hydrolase (sEH) plays an important role in the metabolism of endogenous chemical mediators involved in the regulation of blood pressure and inflammation[1].
Related Catalog	Research Areas >> Inflammation/Immunology
References	[1]. Kim IH, et al. Optimization of amide-based inhibitors of soluble epoxide hydrolase with improved water solubility. J Med Chem. 2005 May 19;48(10):3621-9.