2866508-00-9

2866508-00-9 structure
2866508-00-9 structure
  • Name: Thrombin inhibitor 7
  • Chemical Name: Thrombin inhibitor 7
  • CAS Number: 2866508-00-9
  • Molecular Formula: C26H23N7O2
  • Molecular Weight: 465.51
  • Catalog: Research Areas Metabolic Disease
  • Create Date: 2023-02-03 12:23:47
  • Modify Date: 2024-04-06 12:53:17
  • Thrombin inhibitor 7 is a potent FXIIa inhibitor with IC50 values of 28 nM, >132 µM for FXIIa and FXIa, respectively. Thrombin inhibitor 7 shows low cytotoxicity[1].

Name Thrombin inhibitor 7
Description Thrombin inhibitor 7 is a potent FXIIa inhibitor with IC50 values of 28 nM, >132 µM for FXIIa and FXIa, respectively. Thrombin inhibitor 7 shows low cytotoxicity[1].
Related Catalog
In Vitro Thrombin inhibitor 7 (compound 33b) (0-300 µM; 24 h) shows low cytotoxicity in HepG2, A549 cells[1]. Cell Cytotoxicity Assay[1] Cell Line: HepG2, A549 cells Concentration: 0-300 µM Incubation Time: 24 h Result: Showed low cytotoxicity in HepG2, A549 cells.
References

[1]. Imberg L, et al. Amide-functionalized 1,2,4-Triazol-5-amines as Covalent Inhibitors of Blood Coagulation Factor XIIa and Thrombin. ACS Pharmacol Transl Sci. 2022 Nov 30;5(12):1318-1347.  

Molecular Formula C26H23N7O2
Molecular Weight 465.51