TCS 2312

Modify Date: 2025-10-05 11:30:01

TCS 2312 Structure
TCS 2312 structure
Common Name TCS 2312
CAS Number 838823-31-7 Molecular Weight 412.48
Density N/A Boiling Point N/A
Molecular Formula C25H24N4O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TCS 2312


CHK1-IN-7 (Compound 10c) is a potent human CHK1 inhibitor. CHK1-IN-7 shows no single agent effect, potentiates the antiproliferative effect of Gemcitabine HY-17026 in both prostate and breast cancer cell lines. CHK1-IN-7 can be used for the research of cancer[1].

 Names

Name [1,1'-Biphenyl]-2,4-diol, 4'-[5-[[4-[(cyclopropylamino)methyl]phenyl]amino]-1H-pyrazol-3-yl]
Synonym More Synonyms

 TCS 2312 Biological Activity

Description CHK1-IN-7 (Compound 10c) is a potent human CHK1 inhibitor. CHK1-IN-7 shows no single agent effect, potentiates the antiproliferative effect of Gemcitabine HY-17026 in both prostate and breast cancer cell lines. CHK1-IN-7 can be used for the research of cancer[1].
Related Catalog
References

[1]. Teng M, et al. Structure-based design and synthesis of (5-arylamino-2H-pyrazol-3-yl)-biphenyl-2',4'-diols as novel and potent human CHK1 inhibitors. J Med Chem. 2007 Nov 1;50(22):5253-6.  

 Chemical & Physical Properties

Molecular Formula C25H24N4O2
Molecular Weight 412.48
Exact Mass 412.19000
PSA 93.20000
LogP 5.61440

 Synonyms

TCS 2312
Anpirtoline hydrochloride
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