CBZ-NH-PEG4-CH2CH2COOH

Modify Date: 2024-01-08 17:43:25

CBZ-NH-PEG4-CH2CH2COOH Structure
CBZ-NH-PEG4-CH2CH2COOH structure
Common Name CBZ-NH-PEG4-CH2CH2COOH
CAS Number 756526-00-8 Molecular Weight 399.43546
Density N/A Boiling Point N/A
Molecular Formula C19H29NO8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of CBZ-NH-PEG4-CH2CH2COOH


Cbz-NH-PEG4-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Z-15-aMino-4,7,10,13-tetraoxapentadecacanoic acid
Synonym More Synonyms

 CBZ-NH-PEG4-CH2CH2COOH Biological Activity

Description Cbz-NH-PEG4-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C19H29NO8
Molecular Weight 399.43546

 Safety Information

Hazard Codes Xi

 Synonyms

CBZ-NH-PEG4-CH2CH2COOH