Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Cbz-NH-PEG12-C2-acid
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Purity: 99.0%
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1334177-88-6

1334177-88-6 structure

1334177-88-6 structure

Name: Cbz-NH-PEG12-C2-acid
Chemical Name: amino-dPEG 16-acid
CAS Number: 1334177-88-6
Molecular Formula: C₃₅H₆₁NO₁₆
Molecular Weight: 751.85594
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-06-05 19:00:33
Modify Date: 2025-08-20 16:03:53
Cbz-NH-PEG12-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	amino-dPEG 16-acid
Synonyms	CBZ-NH-PEG12-CH2CH2COOH

Description	Cbz-NH-PEG12-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula	C₃₅H₆₁NO₁₆
Molecular Weight	751.85594

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