Rho Kinase Inhibitor III,Rockout
Modify Date: 2025-08-25 16:29:51
Rho Kinase Inhibitor III,Rockout structure
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Common Name | Rho Kinase Inhibitor III,Rockout | ||
|---|---|---|---|---|
| CAS Number | 7272-84-6 | Molecular Weight | 194.23200 | |
| Density | 1.211g/cm3 | Boiling Point | 406.7ºC at 760 mmHg | |
| Molecular Formula | C13H10N2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 185.2ºC | |
Use of Rho Kinase Inhibitor III,Rockout3-(4-Pyridyl)indole (Rockout) is a Rho-kinase (ROCK) inhibitor, with an IC50 of 25 μM. 3-(4-Pyridyl)indole can inhibit blebbing and cause dissolution of actin stress fibers in a wound healing assay[1]. |
| Name | 3-pyridin-4-yl-1H-indole |
|---|---|
| Synonym | More Synonyms |
| Description | 3-(4-Pyridyl)indole (Rockout) is a Rho-kinase (ROCK) inhibitor, with an IC50 of 25 μM. 3-(4-Pyridyl)indole can inhibit blebbing and cause dissolution of actin stress fibers in a wound healing assay[1]. |
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| Related Catalog | |
| References |
| Density | 1.211g/cm3 |
|---|---|
| Boiling Point | 406.7ºC at 760 mmHg |
| Molecular Formula | C13H10N2 |
| Molecular Weight | 194.23200 |
| Flash Point | 185.2ºC |
| Exact Mass | 194.08400 |
| PSA | 28.68000 |
| LogP | 3.22990 |
| Index of Refraction | 1.688 |
| Storage condition | -20°C |
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~60%
Rho Kinase Inhi... CAS#:7272-84-6 |
| Literature: Chahma; Combellas; Thiebault Synthesis, 1994 , # 4 p. 366 - 368 |
|
~30%
Rho Kinase Inhi... CAS#:7272-84-6 |
| Literature: Beevers, Rebekah E.; Buckley, George M.; Davies, Natasha; Fraser, Joanne L.; Galvin, Francis C.; Hannah, Duncan R.; Haughan, Alan F.; Jenkins, Kerry; Mack, Stephen R.; Pitt, William R.; Ratcliffe, Andrew J.; Richard, Marianna D.; Sabin, Verity; Sharpe, Andrew; Williams, Sophie C. Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 9 p. 2535 - 2538 |
|
~69%
Rho Kinase Inhi... CAS#:7272-84-6 |
| Literature: Lamar, Angus A.; Nicholas, Kenneth M. Tetrahedron, 2009 , vol. 65, # 19 p. 3829 - 3833 |
| rockout |
| 3-(4-Pyridyl)-1H-indole |
| 3-<Pyridyl-(4)>-indol |
| 3-(pyridin-4-yl)-1H-indole |
| 3-(PYRIDIN-4-YL)INDOLE |
| 3-(4-Pyridyl)indole |
| 4-(3-indolyl)-pyridine |
| 1H-Indole, 3-(4-pyridinyl)- |