PDGFRα kinase inhibitor 1
Modify Date: 2025-08-24 14:21:59
PDGFRα kinase inhibitor 1 structure
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Common Name | PDGFRα kinase inhibitor 1 | ||
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| CAS Number | 2209053-93-8 | Molecular Weight | 586.69 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C34H34N8O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of PDGFRα kinase inhibitor 1PDGFRα kinase inhibitor 1 is a highly selective type II PDGFRα kinase inhibitor with IC50s of 132 nM and 6115 nM for PDGFRα and PDGFRβ, respectively[1]. |
| Name | PDGFRα kinase inhibitor 1 |
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| Description | PDGFRα kinase inhibitor 1 is a highly selective type II PDGFRα kinase inhibitor with IC50s of 132 nM and 6115 nM for PDGFRα and PDGFRβ, respectively[1]. |
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| Related Catalog | |
| Target |
PDGFRα:132 nM (IC50) PDGFRβ:6115 nM (IC50) |
| In Vitro | PDGFRα kinase inhibitor 1 (CHMFL-PDGFR-159, Compound 15i) exhibits weak inhibition to DDR1 kinase (IC50: 2462±126 nM)[1]. |
| References |
| Molecular Formula | C34H34N8O2 |
|---|---|
| Molecular Weight | 586.69 |
| InChIKey | NWVOHJOHQOHBMB-UHFFFAOYSA-N |
| SMILES | Cc1ccc(NC(=O)c2ccc(CN(CCN(C)C)C(=O)c3cccnc3)cc2)cc1Nc1nccc(-c2cccnc2)n1 |