p38 MAP Kinase Inhibitor III
Modify Date: 2025-08-25 18:32:19
p38 MAP Kinase Inhibitor III structure
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Common Name | p38 MAP Kinase Inhibitor III | ||
|---|---|---|---|---|
| CAS Number | 581098-48-8 | Molecular Weight | 404.503 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 589.4±60.0 °C at 760 mmHg | |
| Molecular Formula | C23H21FN4S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 310.2±32.9 °C | |
Use of p38 MAP Kinase Inhibitor IIIp38 MAP Kinase Inhibitor III (compound 7h) is a p38 MAPK inhibitor with an 50 of 0.9 μM. p38 MAP Kinase Inhibitor III also inhibits IL-1β and TNF-α release with 50 values of 0.37 μM and 0.044 μM, respectively[1]. |
| Name | (S)-p38 MAP Kinase Inhibitor III |
|---|---|
| Synonym | More Synonyms |
| Description | p38 MAP Kinase Inhibitor III (compound 7h) is a p38 MAPK inhibitor with an 50 of 0.9 μM. p38 MAP Kinase Inhibitor III also inhibits IL-1β and TNF-α release with 50 values of 0.37 μM and 0.044 μM, respectively[1]. |
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| Related Catalog | |
| Target |
p38 MAP kinase:0.9 μM (IC50) |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 589.4±60.0 °C at 760 mmHg |
| Molecular Formula | C23H21FN4S |
| Molecular Weight | 404.503 |
| Flash Point | 310.2±32.9 °C |
| Exact Mass | 404.147095 |
| LogP | 4.78 |
| Vapour Pressure | 0.0±1.7 mmHg at 25°C |
| Index of Refraction | 1.675 |
| InChIKey | VXPWQNBKEIVYIS-HNNXBMFYSA-N |
| SMILES | CSc1nc(-c2ccnc(NC(C)c3ccccc3)c2)c(-c2ccc(F)cc2)[nH]1 |
| (S)-p38 MAPK Inhibitor III |
| 2-Pyridinamine, 4-[5-(4-fluorophenyl)-2-(methylthio)-1H-imidazol-4-yl]-N-[(1S)-1-phenylethyl]- |
| 4-[5-(4-Fluorophenyl)-2-(methylsulfanyl)-1H-imidazol-4-yl]-N-[(1S)-1-phenylethyl]-2-pyridinamine |