DC Chemicals Limited
China
Product Name: ML3403
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: (RS)-4-[5-(4-FLUOROPHENYL)-2-METHYLSULFANYL-3H-IMIDAZOL-4-YL]PYRIDIN-2-YL]-(1-PHENYLETHYL)AMINE]
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

549505-65-9

549505-65-9 structure

549505-65-9 structure

Name: ML 3403
Chemical Name: 4-[4-(4-Fluorophenyl)-2-(methylsulfanyl)-1H-imidazol-5-yl]-N-(1-p henylethyl)-2-pyridinamine
CAS Number: 549505-65-9
Molecular Formula: C₂₃H₂₁FN₄S
Molecular Weight: 404.50300
Catalog: Signaling Pathways MAPK/ERK Pathway p38 MAPK
Create Date: 2017-06-09 20:19:28
Modify Date: 2024-01-12 14:11:57
ML3403 is a potent p38 MAPK inhibitor with an IC50 of 0.38 μM[1].

Name	4-[4-(4-Fluorophenyl)-2-(methylsulfanyl)-1H-imidazol-5-yl]-N-(1-p henylethyl)-2-pyridinamine
Synonyms	p38 MAP inhibitor III

Description	ML3403 is a potent p38 MAPK inhibitor with an IC50 of 0.38 μM[1].
Related Catalog	Signaling Pathways >> MAPK/ERK Pathway >> p38 MAPK Research Areas >> Inflammation/Immunology
References	[1]. Kammerer B, et al. Pharmacokinetics of ML3403 ({4-[5-(4-fluorophenyl)-2-methylsulfanyl-3H-imidazol-4-yl]-pyridin-2-yl}-(1-phenylethyl)-amine), a 4-Pyridinylimidazole-type p38 mitogen-activated protein kinase inhibitor. Drug Metab Dispos. 2007 Jun;35(6):875-83.

Molecular Formula	C₂₃H₂₁FN₄S
Molecular Weight	404.50300
Exact Mass	404.14700
PSA	78.90000
LogP	6.24580

461-87-0 structure

461-87-0

~%

549505-65-9 structure

549505-65-9

Literature: Laufer, Stefan A.; Wagner, Gerd K.; Kotschenreuther, Dunja A.; Albrecht Journal of Medicinal Chemistry, 2003 , vol. 46, # 15 p. 3230 - 3244

116332-54-8 structure

116332-54-8

~%

549505-65-9 structure

549505-65-9

Literature: Laufer, Stefan A.; Wagner, Gerd K.; Kotschenreuther, Dunja A.; Albrecht Journal of Medicinal Chemistry, 2003 , vol. 46, # 15 p. 3230 - 3244

302839-09-4 structure

302839-09-4

~%

549505-65-9 structure

549505-65-9

Literature: Laufer, Stefan A.; Wagner, Gerd K.; Kotschenreuther, Dunja A.; Albrecht Journal of Medicinal Chemistry, 2003 , vol. 46, # 15 p. 3230 - 3244

457081-00-4 structure

457081-00-4

~%

549505-65-9 structure

549505-65-9

Literature: Laufer, Stefan A.; Wagner, Gerd K.; Kotschenreuther, Dunja A.; Albrecht Journal of Medicinal Chemistry, 2003 , vol. 46, # 15 p. 3230 - 3244

618-36-0 structure

618-36-0

549505-59-1 structure

549505-59-1

~39%

549505-65-9 structure

549505-65-9

Literature: Laufer, Stefan A.; Wagner, Gerd K.; Kotschenreuther, Dunja A.; Albrecht Journal of Medicinal Chemistry, 2003 , vol. 46, # 15 p. 3230 - 3244

581098-38-6 structure

581098-38-6

~%

549505-65-9 structure

549505-65-9

Literature: Laufer, Stefan A.; Wagner, Gerd K.; Kotschenreuther, Dunja A.; Albrecht Journal of Medicinal Chemistry, 2003 , vol. 46, # 15 p. 3230 - 3244

Precursor 6
461-87-0 116332-54-8 302839-09-4 618-36-0
549505-59-1 581098-38-6
DownStream 0