ML 3403

Modify Date: 2024-01-12 14:11:57

ML 3403 structure	Common Name	ML 3403
	CAS Number	549505-65-9	Molecular Weight	404.50300
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₃H₂₁FN₄S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of ML 3403

ML3403 is a potent p38 MAPK inhibitor with an IC50 of 0.38 μM[1].

Name	4-[4-(4-Fluorophenyl)-2-(methylsulfanyl)-1H-imidazol-5-yl]-N-(1-p henylethyl)-2-pyridinamine
Synonym	More Synonyms

Description	ML3403 is a potent p38 MAPK inhibitor with an IC50 of 0.38 μM[1].
Related Catalog	Signaling Pathways >> MAPK/ERK Pathway >> p38 MAPK Research Areas >> Inflammation/Immunology
References	[1]. Kammerer B, et al. Pharmacokinetics of ML3403 ({4-[5-(4-fluorophenyl)-2-methylsulfanyl-3H-imidazol-4-yl]-pyridin-2-yl}-(1-phenylethyl)-amine), a 4-Pyridinylimidazole-type p38 mitogen-activated protein kinase inhibitor. Drug Metab Dispos. 2007 Jun;35(6):875-83.

Molecular Formula	C₂₃H₂₁FN₄S
Molecular Weight	404.50300
Exact Mass	404.14700
PSA	78.90000
LogP	6.24580

2-Fluoro-4-meth...

CAS#:461-87-0

ML 3403

CAS#:549505-65-9

Literature: Laufer, Stefan A.; Wagner, Gerd K.; Kotschenreuther, Dunja A.; Albrecht Journal of Medicinal Chemistry, 2003 , vol. 46, # 15 p. 3230 - 3244

4-Fluoro-N-meth...

CAS#:116332-54-8

ML 3403

CAS#:549505-65-9

Literature: Laufer, Stefan A.; Wagner, Gerd K.; Kotschenreuther, Dunja A.; Albrecht Journal of Medicinal Chemistry, 2003 , vol. 46, # 15 p. 3230 - 3244

1-(4-Fluorophen...

CAS#:302839-09-4

ML 3403

CAS#:549505-65-9

Literature: Laufer, Stefan A.; Wagner, Gerd K.; Kotschenreuther, Dunja A.; Albrecht Journal of Medicinal Chemistry, 2003 , vol. 46, # 15 p. 3230 - 3244

2-hydroximino-2...

CAS#:457081-00-4

ML 3403

CAS#:549505-65-9

Literature: Laufer, Stefan A.; Wagner, Gerd K.; Kotschenreuther, Dunja A.; Albrecht Journal of Medicinal Chemistry, 2003 , vol. 46, # 15 p. 3230 - 3244

1-Phenylethanamine

CAS#:618-36-0

2-fluoro-4-[5-(...

CAS#:549505-59-1

~39%

ML 3403

CAS#:549505-65-9

Literature: Laufer, Stefan A.; Wagner, Gerd K.; Kotschenreuther, Dunja A.; Albrecht Journal of Medicinal Chemistry, 2003 , vol. 46, # 15 p. 3230 - 3244

4-(4-fluorophen...

CAS#:581098-38-6

ML 3403

CAS#:549505-65-9

Literature: Laufer, Stefan A.; Wagner, Gerd K.; Kotschenreuther, Dunja A.; Albrecht Journal of Medicinal Chemistry, 2003 , vol. 46, # 15 p. 3230 - 3244

Precursor 6
CAS#:461-87-0 2-Fluoro-4-meth... CAS#:116332-54-8 4-Fluoro-N-meth... CAS#:302839-09-4 1-(4-Fluorophen... CAS#:618-36-0 1-Phenylethanamine
CAS#:549505-59-1 2-fluoro-4-[5-(... CAS#:581098-38-6 4-(4-fluorophen...
DownStream 0

p38 MAP inhibitor III

DC Chemicals Limited
China
Product Name: ML3403
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: (RS)-4-[5-(4-FLUOROPHENYL)-2-METHYLSULFANYL-3H-IMIDAZOL-4-YL]PYRIDIN-2-YL]-(1-PHENYLETHYL)AMINE]
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

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