2-Fluoro-4-methylpyridine

Modify Date: 2025-08-21 11:40:25

2-Fluoro-4-methylpyridine Structure
2-Fluoro-4-methylpyridine structure
Common Name 2-Fluoro-4-methylpyridine
CAS Number 461-87-0 Molecular Weight 111.117
Density 1.1±0.1 g/cm3 Boiling Point 161.4±20.0 °C at 760 mmHg
Molecular Formula C6H6FN Melting Point 160-161 °C (lit.)
MSDS Chinese USA Flash Point 51.4±21.8 °C
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name 2-Fluoro-4-methylpyridine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 161.4±20.0 °C at 760 mmHg
Melting Point 160-161 °C (lit.)
Molecular Formula C6H6FN
Molecular Weight 111.117
Flash Point 51.4±21.8 °C
Exact Mass 111.048424
PSA 12.89000
LogP 1.30
Vapour Pressure 3.0±0.3 mmHg at 25°C
Index of Refraction 1.477
Storage condition Room temperature.

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes Xi:Irritant
Risk Phrases R36/37/38
Safety Phrases S26-S36
RIDADR 1993
WGK Germany 3
Packaging Group III
Hazard Class 3
HS Code 2933399090

 Synthetic Route

~30%

2-Fluoro-4-methylpyridine Structure

2-Fluoro-4-meth...

CAS#:461-87-0

Literature: Puy, Michael Van Der Tetrahedron Letters, 1987 , vol. 28, # 3 p. 255 - 258

~49%

2-Fluoro-4-methylpyridine Structure

2-Fluoro-4-meth...

CAS#:461-87-0

Literature: Ashimori; Ono; Uchida; Ohtaki; Fukaya; Watanabe; Yokoyama Chemical and Pharmaceutical Bulletin, 1990 , vol. 38, # 9 p. 2446 - 2458

~64%

2-Fluoro-4-methylpyridine Structure

2-Fluoro-4-meth...

CAS#:461-87-0

Literature: Shestopalov, Anatoliy M.; Fedorov, Alexander E.; Rodinovskaya, Liudmila A.; Shestopalov, Alexander A.; Gakh, Andrei A. Tetrahedron Letters, 2009 , vol. 50, # 37 p. 5257 - 5259

~22%

2-Fluoro-4-methylpyridine Structure

2-Fluoro-4-meth...

CAS#:461-87-0

Literature: Kiselyov; Strekowski Synthetic Communications, 1994 , vol. 24, # 16 p. 2387 - 2392

~21%

2-Fluoro-4-methylpyridine Structure

2-Fluoro-4-meth...

CAS#:461-87-0

Literature: Kiselyov; Strekowski Synthetic Communications, 1994 , vol. 24, # 16 p. 2387 - 2392

~82%

2-Fluoro-4-methylpyridine Structure

2-Fluoro-4-meth...

CAS#:461-87-0

Literature: Umemoto, Teruo; Tomizawa, Ginjiro Journal of Organic Chemistry, 1989 , vol. 54, # 7 p. 1726 - 1731

 Customs

HS Code 2933399090
Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles6

More Articles
The synthesis of 2-fluoro-4-and 2-fluoro-6-pyridinecarboxylic acid and derivatives. Roe A, et al.

J. Am. Chem. Soc. 71(12) , 4152-4153, (1949)

The13C NMR, UV and IR spectra of 2-fluoropyridine methyl derivatives. Puszko A and Ciurla H.

Chem. Heterocycl. Comp. 35(6) , 677-687, (1999)

2-Fluoro-4-pyridinylmethyl analogues of linopirdine as orally active acetylcholine release-enhancing agents with good efficacy and duration of action. Earl RA, et al.

J. Med. Chem. 41(23) , 4615-4622, (1998)

 Synonyms

4-methyl-2-fluoropyridine
2-Fluor-4-methyl-pyridin
2-fluoro-4-methyl-pyridine
2-Fluoro-4-picoline
2-FLUORO-4-PICOLINE 2-FLUORO-4-METHYLPYRIDINE
2-Fluoro-4-mehtylpyridine
T6NJ BF D1
2-fluoro-4-methlpyridine
2-Fluoro-4-methylpyridine
MFCD00041224
Pyridine, 2-fluoro-4-methyl-
2-fluoropicoline
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