2-Fluoro-4-methylpyridine

Names

[ CAS No. ]:
461-87-0

[ Name ]:
2-Fluoro-4-methylpyridine

[Synonym ]:
4-methyl-2-fluoropyridine
2-Fluor-4-methyl-pyridin
2-fluoro-4-methyl-pyridine
2-Fluoro-4-picoline
2-FLUORO-4-PICOLINE 2-FLUORO-4-METHYLPYRIDINE
2-Fluoro-4-mehtylpyridine
T6NJ BF D1
2-fluoro-4-methlpyridine
2-Fluoro-4-methylpyridine
MFCD00041224
Pyridine, 2-fluoro-4-methyl-
2-fluoropicoline

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
161.4±20.0 °C at 760 mmHg

[ Melting Point ]:
160-161 °C (lit.)

[ Molecular Formula ]:
C₆H₆FN

[ Molecular Weight ]:
111.117

[ Flash Point ]:
51.4±21.8 °C

[ Exact Mass ]:
111.048424

[ PSA ]:
12.89000

[ LogP ]:
1.30

[ Vapour Pressure ]:
3.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.477

[ Storage condition ]:
Room temperature.

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
1993

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ Hazard Class ]:
3

[ HS Code ]:
2933399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

The synthesis of 2-fluoro-4-and 2-fluoro-6-pyridinecarboxylic acid and derivatives. Roe A, et al.

J. Am. Chem. Soc. 71(12) , 4152-4153, (1949)

The13C NMR, UV and IR spectra of 2-fluoropyridine methyl derivatives. Puszko A and Ciurla H.

Chem. Heterocycl. Comp. 35(6) , 677-687, (1999)

2-Fluoro-4-pyridinylmethyl analogues of linopirdine as orally active acetylcholine release-enhancing agents with good efficacy and duration of action. Earl RA, et al.

J. Med. Chem. 41(23) , 4615-4622, (1998)