5-hydroxymethylfurfural

Modify Date: 2024-01-02 12:18:49

5-hydroxymethylfurfural structure	Common Name	5-hydroxymethylfurfural
	CAS Number	67-47-0	Molecular Weight	126.110
	Density	1.3±0.1 g/cm3	Boiling Point	291.5±30.0 °C at 760 mmHg
	Molecular Formula	C₆H₆O₃	Melting Point	28-34 °C(lit.)
	MSDS	Chinese USA	Flash Point	79.4±0.0 °C
	Symbol	GHS07	Signal Word	Warning

Use of 5-hydroxymethylfurfural

5-(Hydroxymethyl)furan-2-carbaldehyde, derived from lignocellulosic biomass, inhibits yeast growth and fermentation as stressors.

Name	5-hydroxymethylfurfural
Synonym	More Synonyms

Description	5-(Hydroxymethyl)furan-2-carbaldehyde, derived from lignocellulosic biomass, inhibits yeast growth and fermentation as stressors.
Related Catalog	Signaling Pathways >> Anti-infection >> Fungal Natural Products >> Acids and Aldehydes Research Areas >> Others
Target	Yeast[1].
In Vitro	It is found that furfural and HMF cause the attenuation of bulk translation activity and the assembly of cytoplasmic mRNP granules in Saccharomyces cerevisiae. Notably, a combination of furfural and HMF induce the remarkable repression of translation initiation and SG formation. Furfural and HMF can induce the formation of cytoplasmic mRNP granules, HMF also causes a gradual reduction in the polysome fraction and a concomitant increase in the 80S monosome fraction[1].
References	[1]. Iwaki A, et al. Biomass conversion inhibitors furfural and 5-hydroxymethylfurfural induce formation of messenger RNP granules and attenuate translation activity in Saccharomyces cerevisiae. Appl Environ Microbiol. 2013 Mar;79(5):1661-7.

Density	1.3±0.1 g/cm3
Boiling Point	291.5±30.0 °C at 760 mmHg
Melting Point	28-34 °C(lit.)
Molecular Formula	C₆H₆O₃
Molecular Weight	126.110
Flash Point	79.4±0.0 °C
Exact Mass	126.031693
PSA	50.44000
LogP	-0.45
Vapour Pressure	0.0±0.6 mmHg at 25°C
Index of Refraction	1.563
Storage condition	2-8°C
Stability	Light Sensitive, Very Hygroscopic

5-hydroxymethylfurfural MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: LT7031100

CHEMICAL NAME :: 2-Furaldehyde, 5-(hydroxymethyl)-

CAS REGISTRY NUMBER :: 67-47-0

BEILSTEIN REFERENCE NO. :: 0110889

LAST UPDATED :: 199712

DATA ITEMS CITED :: 8

MOLECULAR FORMULA :: C6-H6-O3

MOLECULAR WEIGHT :: 126.12

WISWESSER LINE NOTATION :: T5OJ BVH E1Q

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 200 mg/kg

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Kidney, Ureter, Bladder - Kidney tumors

MUTATION DATA

TYPE OF TEST :: Cytogenetic analysis

TEST SYSTEM :: Rodent - hamster Lung

DOSE/DURATION :: 2 gm/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 227,117,1989

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P280-P304 + P340 + P312-P305 + P351 + P338-P337 + P313
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi: Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S26-S36-S24/25
RIDADR	NONH for all modes of transport
WGK Germany	2
RTECS	LT7031100
Packaging Group	III
HS Code	2932190090

Precursor 10
CAS#:87-79-6 L-(−)-Sorbose CAS#:470-23-5 D-fructofuranose CAS#:50-99-7 D-(+)-Glucose CAS#:64-17-5 Ethanol
CAS#:67-56-1 Methanol CAS#:57-48-7 Fructose CAS#:57-50-1 sucrose CAS#:2280-44-6 D-glucopyranose
CAS#:6347-01-9 D-Fructopyranose CAS#:10489-79-9 D-fructofuranose
DownStream 9
CAS#:110339-34-9 2-(dimethoxymet... CAS#:10299-30-6 hexane-1,2,5-triol CAS#:104-80-3 2,5-Anhydro-3,4... CAS#:106-69-4 UNII:W45XXM0XWE
CAS#:65313-46-4 1-hydroxyhexane... CAS#:64-18-6 Formic Acid CAS#:328-50-7 2-Ketoglutaric acid CAS#:110-15-6 Succinic acid
CAS#:4282-32-0 Dimethyl furan-...

HS Code	2932190090
Summary	2932190090 other compounds containing an unfused furan ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

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HMF

EINECS 200-654-9

5-(Hydroxymethyl)furan-2-carboxaldehyde

T5OJ BVH E1Q

5-(Hydroxymethyl)-2-furancarboxaldehyde

5-(Hydroxymethyl)furan-2-carbaldehyde

Aes-103

5-(Hydroxymethyl)furfural

5-Hydroxymethylfurfural

2-Furancarboxaldehyde, 5-(hydroxymethyl)-

MFCD00003234

2-furaldehyde, 5-(hydroxymethyl)-

BioBioPha
China
Product Name: 5-hydroxymethylfurfural
Price: ￥Inquiry/20mg
Purity: 98.0%
Stocking Period: 1 Day
Contact: Xueping-Zheng

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: 5-hydroxymethylfurfural
Price: ￥198.0/20mg ￥158.0/5g ￥568.0/25g
Purity: 98.0%
Stocking Period: 1 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: 5-Hydroxymethylfurfural
Price: $280.0/20mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 5-(Hydroxymethyl)-2-furaldehyde
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Zhejiang Hangyu API Co., Ltd
China
Product Name: 5-Hydroxymethylfurfural
Price: ￥Inquiry/1kg
Purity: 99.5%
Stocking Period: Inquiry
Contact: Vinnie

Henan Tianfu Chemical Co., Ltd.
China
Product Name: 5-Hydroxymethylfurfural
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson

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5-hydroxymethylfurfural

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