SARS-CoV-2-IN-13

Modify Date: 2025-08-25 09:06:32

SARS-CoV-2-IN-13 Structure
SARS-CoV-2-IN-13 structure
Common Name SARS-CoV-2-IN-13
CAS Number 56961-10-5 Molecular Weight 327.12
Density N/A Boiling Point N/A
Molecular Formula C13H8Cl2N2O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of SARS-CoV-2-IN-13


SARS-CoV-2-IN-13 (compound 5) is a potent inhibitor of SARS-CoV-2 with an IC50 of 0.057 μM. SARS-CoV-2-IN-13 is a niclosamide analogue. SARS-CoV-2-IN-13 contains higher stability in human plasma and liver S9 enzymes assay than niclosamide, which can improve bioavailability and half-life when administered orally[1].

 Names

Name SARS-CoV-2-IN-13

 SARS-CoV-2-IN-13 Biological Activity

Description SARS-CoV-2-IN-13 (compound 5) is a potent inhibitor of SARS-CoV-2 with an IC50 of 0.057 μM. SARS-CoV-2-IN-13 is a niclosamide analogue. SARS-CoV-2-IN-13 contains higher stability in human plasma and liver S9 enzymes assay than niclosamide, which can improve bioavailability and half-life when administered orally[1].
Related Catalog
References

[1]. Juang YP, et al. Design, synthesis and biological evaluations of niclosamide analogues against SARS-CoV-2. Eur J Med Chem. 2022 May 5;235:114295.

 Chemical & Physical Properties

Molecular Formula C13H8Cl2N2O4
Molecular Weight 327.12
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