2757763-47-4

2757763-47-4 structure

2757763-47-4 structure

Name: SARS-CoV-2-IN-35
Chemical Name: SARS-CoV-2-IN-35
CAS Number: 2757763-47-4
Molecular Formula: C₂₉H₃₄F₃N₅O₅S
Molecular Weight: 621.67
Catalog: Signaling Pathways Anti-infection SARS-CoV
Create Date: 2023-01-16 09:17:48
Modify Date: 2024-01-16 19:35:10
SARS-CoV-2-IN-35 is a potent and orally active SARS-CoV-2 M pro inhibitor with a Ki value of 12.1 nM. SARS-CoV-2-IN-35 can be used in research of COVID-19[1].

Name	SARS-CoV-2-IN-35

Description	SARS-CoV-2-IN-35 is a potent and orally active SARS-CoV-2 M pro inhibitor with a Ki value of 12.1 nM. SARS-CoV-2-IN-35 can be used in research of COVID-19[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> SARS-CoV
In Vivo	SARS-CoV-2-IN-35 (compound 5; 10 mg/kg; p.o.) has good oral utilization in Wistar-Han rats[1]. Animal Model: Wistar-Han rats[1] Dosage: 10 mg/kg Administration: Oral administration Result: Had oral F of 33 %.
References	[1]. Owen DR, et, al. An oral SARS-CoV-2 Mpro inhibitor clinical candidate for the treatment of COVID-19. Science. 2021 Dec 24;374(6575):1586-1593.

Molecular Formula	C₂₉H₃₄F₃N₅O₅S
Molecular Weight	621.67