1017691-52-9

1017691-52-9 structure

Name: SARS-CoV-2-IN-31
Chemical Name: SARS-CoV-2-IN-31
CAS Number: 1017691-52-9
Molecular Formula: C₂₉H₂₈N₄O₂
Molecular Weight: 464.56
Catalog: Signaling Pathways Anti-infection SARS-CoV
Create Date: 2022-10-24 18:28:18
Modify Date: 2025-08-23 09:07:15
SARS-CoV-2-IN-31 is an effective COVID-19 inhibitor. SARS-CoV-2-IN-31 exhibits excellent to mild activity against various cancer cell lines with IC50 values range from 28.84 to 38.36 μM. SARS-CoV-2-IN-31 can be used for the research of cancer[1].

Name	SARS-CoV-2-IN-31

Description	SARS-CoV-2-IN-31 is an effective COVID-19 inhibitor. SARS-CoV-2-IN-31 exhibits excellent to mild activity against various cancer cell lines with IC50 values range from 28.84 to 38.36 μM. SARS-CoV-2-IN-31 can be used for the research of cancer[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Anti-infection >> SARS-CoV
Target	IC50: 38.36 μM (MCF-7); 38.46 μM (MDA-MB-231); 28.84 μM (HeLa); 30.62 μM (PC-3); ＞40 μM (Ishikawa)[1]
In Vitro	SARS-CoV-2-IN-31 exhibits antiproliferative activity in five different human cancer cell lines with IC50 values of 38.36 μM (MCF-7), 38.46 μM (MDA-MB-231), 28.84 μM (HeLa), 30.62 μM (PC-3) and ＞40 μM (Ishikawa), respectively[1]. SARS-CoV-2-IN-31 shows comparatively high binding affinity with value of -8.3 Kcal/mole[1]
References	[1]. Anamika Gupta, et al. Visible Light-Promoted Green and Sustainable Approach for One-Pot Synthesis of 4,4’-(Arylmethylene)bis(1H-pyrazol-5-ols), In Vitro Anticancer Activity, and Molecular Docking with Covid-19 Mpro. ACS Omega 2022.

Molecular Formula	C₂₉H₂₈N₄O₂
Molecular Weight	464.56