SARS-CoV-2-IN-31

Modify Date: 2024-01-19 05:36:22

SARS-CoV-2-IN-31 Structure
SARS-CoV-2-IN-31 structure
Common Name SARS-CoV-2-IN-31
CAS Number 1017691-52-9 Molecular Weight 464.56
Density N/A Boiling Point N/A
Molecular Formula C29H28N4O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of SARS-CoV-2-IN-31


SARS-CoV-2-IN-31 is an effective COVID-19 inhibitor. SARS-CoV-2-IN-31 exhibits excellent to mild activity against various cancer cell lines with IC50 values range from 28.84 to 38.36 μM. SARS-CoV-2-IN-31 can be used for the research of cancer[1].

 Names

Name SARS-CoV-2-IN-31

 SARS-CoV-2-IN-31 Biological Activity

Description SARS-CoV-2-IN-31 is an effective COVID-19 inhibitor. SARS-CoV-2-IN-31 exhibits excellent to mild activity against various cancer cell lines with IC50 values range from 28.84 to 38.36 μM. SARS-CoV-2-IN-31 can be used for the research of cancer[1].
Related Catalog
Target

IC50: 38.36 μM (MCF-7); 38.46 μM (MDA-MB-231); 28.84 μM (HeLa); 30.62 μM (PC-3); >40 μM (Ishikawa)[1]

In Vitro SARS-CoV-2-IN-31 exhibits antiproliferative activity in five different human cancer cell lines with IC50 values of 38.36 μM (MCF-7), 38.46 μM (MDA-MB-231), 28.84 μM (HeLa), 30.62 μM (PC-3) and >40 μM (Ishikawa), respectively[1]. SARS-CoV-2-IN-31 shows comparatively high binding affinity with value of -8.3 Kcal/mole[1]
References

[1]. Anamika Gupta, et al. Visible Light-Promoted Green and Sustainable Approach for One-Pot Synthesis of 4,4’-(Arylmethylene)bis(1H-pyrazol-5-ols), In Vitro Anticancer Activity, and Molecular Docking with Covid-19 Mpro. ACS Omega 2022.

 Chemical & Physical Properties

Molecular Formula C29H28N4O2
Molecular Weight 464.56