SARS-CoV-2-IN-22

Modify Date: 2025-08-27 03:31:49

SARS-CoV-2-IN-22 Structure
SARS-CoV-2-IN-22 structure
Common Name SARS-CoV-2-IN-22
CAS Number 2710278-53-6 Molecular Weight 456.56
Density N/A Boiling Point N/A
Molecular Formula C27H24N2O3S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of SARS-CoV-2-IN-22


SARS-CoV-2-IN-22 is a SARS-CoV-2 pseudovirus entry inhibitor with an IC50 value of 16.96 µM[1].

 Names

Name SARS-CoV-2-IN-22

 SARS-CoV-2-IN-22 Biological Activity

Description SARS-CoV-2-IN-22 is a SARS-CoV-2 pseudovirus entry inhibitor with an IC50 value of 16.96 µM[1].
Related Catalog
Target

IC50: 16.96 µM (SARS-CoV-2)[1]

In Vitro SARS-CoV-2-IN-22 (Compound 9a) effectively blocks the binding of SARS-CoV-2 to the host ACE2 receptor through dual recognition of SARS-CoV-2 spike receptor-binding domain (RBD) and human ACE2. SARS-CoV-2-IN-2 displays no cytotoxicity to normal cells (LO2)[1].
References

[1]. Ting Xu, et al. Discovery of honokiol thioethers containing 1,3,4-oxadiazole moieties as potential α-glucosidase and SARS-CoV-2 entry inhibitors. Bioorg Med Chem. 2022 Aug 1;67:116838.

 Chemical & Physical Properties

Molecular Formula C27H24N2O3S
Molecular Weight 456.56
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