SARS-CoV-2-IN-10 structure
|
Common Name | SARS-CoV-2-IN-10 | ||
|---|---|---|---|---|
| CAS Number | 2722634-95-7 | Molecular Weight | 521.60 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C27H37F2N3O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of SARS-CoV-2-IN-10SARS-CoV-2-IN-10 is a potent and nontoxic inhibitor of SARS-CoV-2 3CL protease (3CLpro) with an IC50 and EC50 of 0.13 and 1.03 nM, respectively. SARS-CoV-2 3C-like protease (3CLpro), an enzyme essential for viral replication, is an attractive target for therapeutic intervention. SARS-CoV-2-IN-11 may lead to the emergence of effective SARS-CoV-2-specific antivirals[1]. |
| Name | SARS-CoV-2-IN-10 |
|---|
| Description | SARS-CoV-2-IN-10 is a potent and nontoxic inhibitor of SARS-CoV-2 3CL protease (3CLpro) with an IC50 and EC50 of 0.13 and 1.03 nM, respectively. SARS-CoV-2 3C-like protease (3CLpro), an enzyme essential for viral replication, is an attractive target for therapeutic intervention. SARS-CoV-2-IN-11 may lead to the emergence of effective SARS-CoV-2-specific antivirals[1]. |
|---|---|
| Related Catalog | |
| Target |
SARS-CoV-2 3C-like proteas[1] |
| References |
| Molecular Formula | C27H37F2N3O5 |
|---|---|
| Molecular Weight | 521.60 |
| InChIKey | QMWZWHYKVZAETM-FDWBJODVSA-N |
| SMILES | CC(C)CC(NC(=O)OC(c1ccccc1)C1CCC(F)(F)CC1)C(=O)NC(C=O)CC1CCNC1=O |