PknB-IN-2

Modify Date: 2025-12-08 17:59:57

PknB-IN-2 Structure
PknB-IN-2 structure
Common Name PknB-IN-2
CAS Number 500015-22-5 Molecular Weight 460.56
Density N/A Boiling Point N/A
Molecular Formula C28H32N2O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PknB-IN-2


PknB-IN-2 (Compound 10) is a Mycobacterium tuberculosis protein kinase B (PknB) inhibitor with an IC50 of 12.1 μM[1].

 Names

Name PknB-IN-2

 PknB-IN-2 Biological Activity

Description PknB-IN-2 (Compound 10) is a Mycobacterium tuberculosis protein kinase B (PknB) inhibitor with an IC50 of 12.1 μM[1].
Related Catalog
Target

IC50: 12.1 μM (PknB)[1]

In Vitro PknB-IN-2 (Compound 10) shows encouraging growth inhibition activity toward the M. tuberculosis H37Rv strain, with a MIC value of 6.2 μg/mL[1].
References

[1]. Thongdee P, et al. Virtual Screening Identifies Novel and Potent Inhibitors of Mycobacterium tuberculosis PknB with Antibacterial Activity. J Chem Inf Model. 2022 Aug 22.

 Chemical & Physical Properties

Molecular Formula C28H32N2O4
Molecular Weight 460.56
InChIKey RRABSVSVBDUTFJ-UHFFFAOYSA-N
SMILES Cc1ccc2c(c1)c(-c1ccccc1)c(-c1ccccc1)n2CC(O)CNC(CO)(CO)CO
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