PknB-IN-1
Modify Date: 2025-08-22 06:48:50
PknB-IN-1 structure
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Common Name | PknB-IN-1 | ||
|---|---|---|---|---|
| CAS Number | 1447917-39-6 | Molecular Weight | 390.52 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C25H30N2O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of PknB-IN-1PknB-IN-1 (Compound 2) is a protein kinase B (PknB) inhibitor (IC50=14.4 μM). PknB-IN-1 shows anti-mycobacterial activity, can inhibit M. tuberculosis H37Rv strain growth (MIC=6.2 μg/mL)[1]. |
| Name | PknB-IN-1 |
|---|
| Description | PknB-IN-1 (Compound 2) is a protein kinase B (PknB) inhibitor (IC50=14.4 μM). PknB-IN-1 shows anti-mycobacterial activity, can inhibit M. tuberculosis H37Rv strain growth (MIC=6.2 μg/mL)[1]. |
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| Related Catalog | |
| Target |
IC50: 14.4 μM (PknB)[1] |
| In Vitro | PknB-IN-1 (0-100 μM; 60 min) can inhibit M. tuberculosis PknB activity[1]. Cell Viability Assay[1] Cell Line: M. tuberculosis Concentration: 0-100 μM Incubation Time: 60 min Result: Exhibited M. tuberculosis PknB inhibition activity (IC50=7.3 μM). |
| References |
| Molecular Formula | C25H30N2O2 |
|---|---|
| Molecular Weight | 390.52 |
| InChIKey | GWEHFYMAEAZCBW-CCEZHUSRSA-N |
| SMILES | CCCCN(C)CC(O)Cn1cc(C=CC(=O)c2ccccc2)c2ccccc21 |