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500015-22-5

500015-22-5 structure

500015-22-5 structure

Name: PknB-IN-2
Chemical Name: PknB-IN-2
CAS Number: 500015-22-5
Molecular Formula: C₂₈H₃₂N₂O₄
Molecular Weight: 460.56
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2022-10-12 19:59:20
Modify Date: 2024-01-14 14:10:03
PknB-IN-2 (Compound 10) is a Mycobacterium tuberculosis protein kinase B (PknB) inhibitor with an IC50 of 12.1 μM[1].

Name	PknB-IN-2

Description	PknB-IN-2 (Compound 10) is a Mycobacterium tuberculosis protein kinase B (PknB) inhibitor with an IC50 of 12.1 μM[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
Target	IC50: 12.1 μM (PknB)[1]
In Vitro	PknB-IN-2 (Compound 10) shows encouraging growth inhibition activity toward the M. tuberculosis H37Rv strain, with a MIC value of 6.2 μg/mL[1].
References	[1]. Thongdee P, et al. Virtual Screening Identifies Novel and Potent Inhibitors of Mycobacterium tuberculosis PknB with Antibacterial Activity. J Chem Inf Model. 2022 Aug 22.

Molecular Formula	C₂₈H₃₂N₂O₄
Molecular Weight	460.56