UNII:H1547KG7UZ

Modify Date: 2024-01-10 09:44:20

UNII:H1547KG7UZ Structure
UNII:H1547KG7UZ structure
Common Name UNII:H1547KG7UZ
CAS Number 498-21-5 Molecular Weight 132.115
Density 1.3±0.1 g/cm3 Boiling Point 236.5±13.0 °C at 760 mmHg
Molecular Formula C5H8O4 Melting Point 110-115 °C(lit.)
MSDS Chinese USA Flash Point 111.1±16.3 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of UNII:H1547KG7UZ


2-Methylsuccinic acid is a normal metabolite in human fluids and the main biochemical measurable features in ethylmalonic encephalopathy.

 Names

Name 2-Methylsuccinic acid
Synonym More Synonyms

 UNII:H1547KG7UZ Biological Activity

Description 2-Methylsuccinic acid is a normal metabolite in human fluids and the main biochemical measurable features in ethylmalonic encephalopathy.
Related Catalog
Target

Human Endogenous Metabolite

In Vitro 2-Methylsuccinic acid is a normal metabolite in human fluids and the main biochemical measurable features in ethylmalonic encephalopathy[1]. The underlying biochemical defect involves isoleucine catabolism[2].
References

[1]. Grosso S, et al. Ethylmalonic encephalopathy: further clinical and neuroradiological characterization. J Neurol. 2002 Oct;249(10):1446-50.

[2]. Nowaczyk MJ, et al. Ethylmalonic and methylsuccinic aciduria in ethylmalonic encephalopathy arise from abnormal isoleucine metabolism. Metabolism. 1998 Jul;47(7):836-9.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 236.5±13.0 °C at 760 mmHg
Melting Point 110-115 °C(lit.)
Molecular Formula C5H8O4
Molecular Weight 132.115
Flash Point 111.1±16.3 °C
Exact Mass 132.042252
PSA 74.60000
LogP -0.24
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.474
Stability Stable. Combustible. Incompatible with bases, oxidizing agents, reducing agents.

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi:Irritant
Risk Phrases R36/37/38
Safety Phrases S26-S36
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2917190090

 Synthetic Route

 Customs

HS Code 2917190090
Summary 2917190090 acyclic polycarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

 Articles24

More Articles
Age-related reference values for urinary organic acids in a healthy Turkish pediatric population.

Clin. Chem. 40(6) , 862-6, (1994)

Organic acid concentrations were quantified by gas chromatography and the individual acids identified by mass spectrometry in urine specimens from a healthy Turkish pediatric population of ages 2 days...

SPE-NMR metabolite sub-profiling of urine.

Anal. Bioanal. Chem 404(8) , 2349-61, (2012)

NMR-based metabolite profiling of urine is a fast and reproducible method for detection of numerous metabolites with diverse chemical properties. However, signal overlap in the (1)H NMR profiles of hu...

Concentrations of riboflavin and related organic acids in children with protein-energy malnutrition.

Am. J. Clin. Nutr. 71(4) , 978-86, (2000)

Riboflavin, flavin mononucleotide (FMN), and flavin adenine dinucleotide (FAD) concentrations have been little studied in cases of malnutrition.Our objective was to investigate the effects of malnutri...

 Synonyms

UNII:H1547KG7UZ
d-Methylsuccinic acid
2-methylbutanedioic acid
2-Methylsuccinic acid
Pyrotartaric Acid
METHYLSUCCINIC ACID
MFCD00002659
Butanedioic acid, 2-methyl-
EINECS 207-857-1
Methylbutanedioic acid
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