Citraconic acid

Modify Date: 2024-01-05 09:23:17

Citraconic acid Structure
Citraconic acid structure
Common Name Citraconic acid
CAS Number 498-23-7 Molecular Weight 130.09900
Density 1,62 g/cm3 Boiling Point 336ºC
Molecular Formula C5H6O4 Melting Point 88-94 °C(lit.)
MSDS Chinese USA Flash Point N/A
Symbol GHS07
GHS07
Signal Word Warning

 Use of Citraconic acid


Citraconic acid belongs to the class of organic compounds known as methyl-branched fatty acids.

 Names

Name citraconic acid
Synonym More Synonyms

 Citraconic acid Biological Activity

Description Citraconic acid belongs to the class of organic compounds known as methyl-branched fatty acids.
Related Catalog
Target

Human Endogenous Metabolite

References

[1]. Pulat M, et al. Lipase release through semi-interpenetrating polymer network hydrogels based on chitosan, acrylamide, and citraconic acid. Artif Cells Nanomed Biotechnol. 2014 Apr;42(2):121-7.

 Chemical & Physical Properties

Density 1,62 g/cm3
Boiling Point 336ºC
Melting Point 88-94 °C(lit.)
Molecular Formula C5H6O4
Molecular Weight 130.09900
Exact Mass 130.02700
PSA 74.60000
LogP 0.10190
Vapour Pressure 2.09E-05mmHg at 25°C
Water Solubility FREELY SOLUBLE

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
GE6650000
CHEMICAL NAME :
Citraconic acid
CAS REGISTRY NUMBER :
498-23-7
BEILSTEIN REFERENCE NO. :
1722679
LAST UPDATED :
199612
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C5-H6-O4
MOLECULAR WEIGHT :
130.11
WISWESSER LINE NOTATION :
QVY1&U1VQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1320 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - tremor Gastrointestinal - ulceration or bleeding from stomach
REFERENCE :
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 2,327,1964
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2260 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - dyspnea Gastrointestinal - other changes
REFERENCE :
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 2,327,1964
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
1350 mg/kg
TOXIC EFFECTS :
Gastrointestinal - gastritis
REFERENCE :
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 2,327,1964

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn:Harmful;
Risk Phrases R22;R36/37/38
Safety Phrases S36-S37/39-S26
RIDADR 2811
WGK Germany 3
RTECS GE6650000
Packaging Group III
Hazard Class 6.1(b)
HS Code 2917190090

 Synthetic Route

 Customs

HS Code 2917190090
Summary 2917190090 acyclic polycarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

 Articles28

More Articles
Highly sensitive GC/MS/MS method for quantitation of amino and nonamino organic acids.

Anal. Chem. 83(7) , 2705-11, (2011)

Metabolite profiling methods are important tools for measurement of metabolite pools in biological systems. While most metabolite profiling methods report relative intensities or depend on a few inter...

The antipsoriatic agent monomethylfumarate has antiproliferative, prodifferentiative, and anti-inflammatory effects on keratinocytes.

J. Pharmacol. Exp. Ther. 352(1) , 90-7, (2015)

Monomethylfumarate (MMF) is thought to be the bioactive ingredient of the drug Fumaderm (Biogen Idec, Cambridge, MA), licensed in Germany since 1994 for the treatment of moderate-to-severe psoriasis. ...

Effects of fumaric acid esters on blood-brain barrier tight junction proteins.

Neurosci. Lett. 555 , 165-70, (2013)

The blood-brain barrier (BBB) is composed of a network of tight junctions (TJ) which interconnect cerebral endothelial cells (EC). Alterations in the TJ proteins are common in inflammatory diseases of...

 Synonyms

EINECS 207-858-7
Maleic acid,methyl
cis-2-methylbutenedioic acid
2-Methylmaleic acid
Citraconicacid
Kyselina citrakonova
methyl-maleicaci
METHYLMALEIC ACID
Citraconic acid
2-methyl-2-butenedioic acid
cis-methylbutenedioic acid
Citraconic
MFCD00078086
(Z)-2-methyl-2-butenedioic acid
Top Suppliers:I want be here



Get all suppliers and price by the below link:

Citraconic acid suppliers


Price: ¥550/10 mM * 1 mL in DMSO

Reference only. check more Citraconic acid price