Mesaconic acid
Mesaconic acid structure
|
Common Name | Mesaconic acid | ||
|---|---|---|---|---|
| CAS Number | 498-24-8 | Molecular Weight | 130.09900 | |
| Density | 1.387 g/cm3 | Boiling Point | 336.6ºC at 760 mmHg | |
| Molecular Formula | C5H6O4 | Melting Point | 200-202ºC | |
| MSDS | Chinese USA | Flash Point | 171.5ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of Mesaconic acidMesaconic acid is used as a fire retardant, as recent studies revealed this acid is a competitive inhibitor of fumarate reduction. |
| Name | mesaconic acid |
|---|---|
| Synonym | More Synonyms |
| Density | 1.387 g/cm3 |
|---|---|
| Boiling Point | 336.6ºC at 760 mmHg |
| Melting Point | 200-202ºC |
| Molecular Formula | C5H6O4 |
| Molecular Weight | 130.09900 |
| Flash Point | 171.5ºC |
| Exact Mass | 130.02700 |
| PSA | 74.60000 |
| LogP | 0.10190 |
| Vapour Pressure | 0mmHg at 25°C |
| Index of Refraction | 1.514 |
| Storage condition | 2-8°C |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi:Irritant; |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26-S36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | OX5075000 |
| HS Code | 2917190090 |
| Precursor 10 | |
|---|---|
| DownStream 10 | |
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CAS#:20537-97-7| HS Code | 2917190090 |
|---|---|
| Summary | 2917190090 acyclic polycarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0% |
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The antipsoriatic agent monomethylfumarate has antiproliferative, prodifferentiative, and anti-inflammatory effects on keratinocytes.
J. Pharmacol. Exp. Ther. 352(1) , 90-7, (2015) Monomethylfumarate (MMF) is thought to be the bioactive ingredient of the drug Fumaderm (Biogen Idec, Cambridge, MA), licensed in Germany since 1994 for the treatment of moderate-to-severe psoriasis. ... |
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In vitro pharmacokinetics of anti-psoriatic fumaric acid esters.
BMC Pharmacol. 4 , 22, (2004) Psoriasis is a chronic inflammatory skin disease that can be successfully treated with a mixture of fumaric acid esters (FAE) formulated as enteric-coated tablets for oral use. These tablets consist o... |
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The psoriasis drug monomethylfumarate is a potent nicotinic acid receptor agonist.
Biochem. Biophys. Res. Commun. 375(4) , 562-5, (2008) Nicotinic acid has been used for several decades to treat dyslipidemia. In mice, the lipid-lowing effect of nicotinic acid is mediated by the Gi coupled receptor PUMA-G. In humans, high (GPR109A) and ... |
| Methylfumaric Acid |
| EINECS 207-859-2 |
| Mesaconic Acid |
| MFCD00002653 |
| 2-Butenedioic acid,2-methyl-, (2E)- |
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: Mesaconic acid
- Price: ￥1018.0/10g ￥2038.0/25g ￥5418.0/100g
- Purity: 97.0%
- Stocking Period: 1 Day
- Contact: Liu jia
- DC Chemicals Limited
- China
- Product Name: Mesaconic acid
- Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: Mesaconic acid
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
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