UNII:FGB8O5N903

Modify Date: 2024-01-02 07:08:53

UNII:FGB8O5N903 Structure
UNII:FGB8O5N903 structure
Common Name UNII:FGB8O5N903
CAS Number 78-75-1 Molecular Weight 201.888
Density 1.9±0.1 g/cm3 Boiling Point 140.4±8.0 °C at 760 mmHg
Molecular Formula C3H6Br2 Melting Point -55 °C
MSDS Chinese USA Flash Point 21.9±17.7 °C
Symbol GHS02 GHS07
GHS02, GHS07
Signal Word Warning

 Names

Name 1,2-Dibromopropane
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.9±0.1 g/cm3
Boiling Point 140.4±8.0 °C at 760 mmHg
Melting Point -55 °C
Molecular Formula C3H6Br2
Molecular Weight 201.888
Flash Point 21.9±17.7 °C
Exact Mass 199.883606
LogP 2.43
Vapour Pressure 7.7±0.2 mmHg at 25°C
Index of Refraction 1.511
Stability Stable. Flammable. Incompatible with strong oxidizing agents, strong bases, magnesium.
Water Solubility slightly soluble

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TX8574000
CHEMICAL NAME :
Propane, 1,2-dibromo-
CAS REGISTRY NUMBER :
78-75-1
BEILSTEIN REFERENCE NO. :
1718884
LAST UPDATED :
199709
DATA ITEMS CITED :
11
MOLECULAR FORMULA :
C3-H6-Br2
MOLECULAR WEIGHT :
201.91
WISWESSER LINE NOTATION :
EY1&1E

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
741 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
12 gm/m3/4H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
676 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
75 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
Sex chromosome loss and nondisjunction

MUTATION DATA

TEST SYSTEM :
Rodent - rat
DOSE/DURATION :
75716 ug/kg
REFERENCE :
CRTOEC Chemical Research in Toxicology. (American Chemical Soc., Distribution Office Dept. 223, POB 57/36, West End Station, Washington, DC 20037) V.1- 1988- Volume(issue)/page/year: 4,528,1991 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 5 mg/m3 JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X6607 No. of Facilities: 7 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 1822 (estimated) No. of Female Employees: 272 (estimated)

 Safety Information

Symbol GHS02 GHS07
GHS02, GHS07
Signal Word Warning
Hazard Statements H226-H302 + H332
Personal Protective Equipment Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes Xn:Harmful;
Risk Phrases R10;R20/21/22;R36/37/38
Safety Phrases S23-S24/25-S36/37/39-S26-S16
RIDADR UN 1993 3/PG 3
WGK Germany 3
RTECS TX8574000
Packaging Group III
Hazard Class 3
HS Code 29033036

 Synthetic Route

 Preparation

78-75-1 preparation

 Customs

HS Code 29033036

 Articles12

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J. Chromatogr. A. 1408 , 22-9, (2015)

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[Research concerning rutin semisynthetic derivatives. Synthesis, physico-chemical and microbiological characterisation of some new rutin-isoniazid derivatives].

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Isoniazid is one of the most used antituberculosis drugs, but its toxicity is high. In this study, four derivatives of rutin and isoniazid were prepared and their antibacterial and antimycotic activit...

 Synonyms

1,2-dibromo-propan
1,2-dibromoprpane
Propane, 1,2-dibromo-
1,2-Dobromopropane
Propylene dibromide
2-Bromopropionyl bromide
1,2-Dibrompropan
1,2-Dibromopropane
CH2BrCHBrCH3
2,3-dibromopropane
UNII:FGB8O5N903
EINECS 201-139-1
11,2-DIBROMOPROPANE
MFCD00000148
PROPYLENE BROMIDE
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