NSD3-IN-3
Modify Date: 2025-09-18 18:58:02
NSD3-IN-3 structure
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Common Name | NSD3-IN-3 | ||
|---|---|---|---|---|
| CAS Number | 445416-12-6 | Molecular Weight | 331.39 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C15H17N5O2S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of NSD3-IN-3NSD3-IN-3 is a potent NSD3 inhibtor with an IC50 value of 1.86 μM. NSD3-IN-3 has anticancer activity and significantly inhibits the growth and proliferation of non-small cell lung cancer cell line H460[1]. |
| Name | NSD3-IN-3 |
|---|
| Description | NSD3-IN-3 is a potent NSD3 inhibtor with an IC50 value of 1.86 μM. NSD3-IN-3 has anticancer activity and significantly inhibits the growth and proliferation of non-small cell lung cancer cell line H460[1]. |
|---|---|
| Related Catalog | |
| Target |
NSD3:1.86 μM (IC50) |
| In Vitro | NSD3-IN-3 (化合物 B2) (0-10 μM; 48 h) 在 10 μM 下完全抑制 H460 和 H1299 细胞中 H3K36me3 修饰[1]。 NSD3-IN-3 (0-20 μM; 48 h) 抑制 H460 细胞的生长[1]。 Cell Viability Assay[1] Cell Line: Non-small cell lung cancer cell line H460 Concentration: 0, 2.5, 5, 10, and 20 μM Incubation Time: 48 hours Result: Inhibited cell growth dose-dependently. |
| References |
| Molecular Formula | C15H17N5O2S |
|---|---|
| Molecular Weight | 331.39 |
| InChIKey | CPVQNKHOVSEOTA-UHFFFAOYSA-N |
| SMILES | CCOc1ccc(OCCn2c(=S)[nH]c3c(N)ncnc32)cc1 |