ATR-IN-14 structure
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Common Name | ATR-IN-14 | ||
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CAS Number | 2765785-88-2 | Molecular Weight | 393.42 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C20H20FN7O | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of ATR-IN-14ATR-IN-14 (compound 1) is a potent ATR kinase inhibitor. ATR-IN-14 inhibits ATR signaling pathways downstream CHKI protein phosphorylation, with inhibition of 98.03% at 25 nM. ATR-IN-14 shows good anticancer activity in LoVo cells, with an IC50 of 64 nM[1]. |
Name | ATR-IN-14 |
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Description | ATR-IN-14 (compound 1) is a potent ATR kinase inhibitor. ATR-IN-14 inhibits ATR signaling pathways downstream CHKI protein phosphorylation, with inhibition of 98.03% at 25 nM. ATR-IN-14 shows good anticancer activity in LoVo cells, with an IC50 of 64 nM[1]. |
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Related Catalog | |
Target |
ATR |
References |
[1]. Shao-hui Wang, et al. Class of 1,7-naphthyridine compounds and application thereof. WO2022063308A1. |
Molecular Formula | C20H20FN7O |
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Molecular Weight | 393.42 |