ATR-IN-15

Modify Date: 2025-08-25 08:26:25

ATR-IN-15 structure	Common Name	ATR-IN-15
	CAS Number	2756665-52-6	Molecular Weight	378.43
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₉H₂₂N₈O	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of ATR-IN-15

ATR-IN-15 (compound 1) is an orally active and potent ATR kinase inhibitor, with an IC50 of 8 nM. ATR-IN-15 also inhibits human colon tumor cells LoVo, DNA-PK and PI3K, with IC50 values of 47, 663 and 5131 nM, respectively[1].

Name	ATR-IN-15

Description	ATR-IN-15 (compound 1) is an orally active and potent ATR kinase inhibitor, with an IC50 of 8 nM. ATR-IN-15 also inhibits human colon tumor cells LoVo, DNA-PK and PI3K, with IC50 values of 47, 663 and 5131 nM, respectively[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> ATM/ATR Signaling Pathways >> Cell Cycle/DNA Damage >> DNA-PK Signaling Pathways >> PI3K/Akt/mTOR >> PI3K Signaling Pathways >> PI3K/Akt/mTOR >> ATM/ATR Signaling Pathways >> PI3K/Akt/mTOR >> DNA-PK
Target	ATR:8 nM (IC50) PI3K:5131 nM (IC50) ATM:> 10000 nM (IC50)
References	[1]. Xin Li, et al. Imidazopyrimidine derivative, preparation method therefor and medical use thereof. WO2022002243A1.

Molecular Formula	C₁₉H₂₂N₈O
Molecular Weight	378.43

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ATR-IN-15

Use of ATR-IN-15

Names

ATR-IN-15 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.