Minaprine

Modify Date: 2024-01-21 07:00:45

Minaprine Structure
Minaprine structure
Common Name Minaprine
CAS Number 25905-77-5 Molecular Weight 298.38
Density 1.156g/cm3 Boiling Point 531.2ºC at 760 mmHg
Molecular Formula C17H22N4O Melting Point 122°
MSDS Chinese USA Flash Point 275.1ºC
Symbol GHS07
GHS07
Signal Word Warning

 Use of Minaprine


Minaprine is a reversible inhibitor of MAO-A; weakly inhibit acetylcholinesterase; an antidepressant for treatment of depression.

 Names

Name minaprine
Synonym More Synonyms

 Minaprine Biological Activity

Description Minaprine is a reversible inhibitor of MAO-A; weakly inhibit acetylcholinesterase; an antidepressant for treatment of depression.
Related Catalog
References

[1]. Kan JP, et al. Effect of the antidepressant minaprine on both forms of monoamine oxidase in the rat. Biochem Pharmacol. 1986 Mar 15;35(6):973-8.

[2]. Contreras JM, et al. Aminopyridazines as acetylcholinesterase inhibitors. J Med Chem. 1999 Feb 25;42(4):730-41.

 Chemical & Physical Properties

Density 1.156g/cm3
Boiling Point 531.2ºC at 760 mmHg
Melting Point 122°
Molecular Formula C17H22N4O
Molecular Weight 298.38
Flash Point 275.1ºC
PSA 50.28000
LogP 3.81100
Vapour Pressure 2.29E-11mmHg at 25°C
Index of Refraction 1.595
Storage condition -20℃

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn
Risk Phrases 22
Safety Phrases 36
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS QE3477830
HS Code 2934999090

 Customs

HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles25

More Articles
Multicentric double-blind study comparing efficacy and safety of minaprine and imipramine in dysthymic disorders.

Neuropsychobiology 31(2) , 68-75, (1995)

This multicentre study compares the therapeutic efficacy and safety of minaprine (200 mg) to that of imipramine (50, 75, 100 mg) in the treatment of patients over 40 years suffering from dysthymic dis...

Computerised psychomotor performance testing: a comparative study of the single dose pharmacodynamics of minaprine and amitriptyline in young and elderly subjects.

Br. J. Clin. Pharmacol. 36(4) , 376-9, (1993)

The psychomotor and cardiovascular effects of minaprine 100 mg, a novel antidepressant, were compared with amitriptyline 25 mg, as a positive control, and placebo in a single dose randomised double-bl...

Cholinomimetic activity of minaprine is related to the amelioration of delayed neuronal death in gerbils.

Physiol. Behav. 52(1) , 141-7, (1992)

We attempted to determine if the cholinomimetic activity of the psychotropic drug minaprine was related to the amelioration of the delayed neuronal death induced by cerebral ischemia in Mongolian gerb...

 Synonyms

TS-370
Minaprin diHCl
MINAPRIN DIHYDROCHLORIDE
MINAPRINE HYDROCHLORIDE
MINAPRINE DIHYDROCHLORIDE
minaprin
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