2-Morpholinoethanamine

Modify Date: 2024-01-02 14:43:56

2-Morpholinoethanamine Structure
2-Morpholinoethanamine structure
Common Name 2-Morpholinoethanamine
CAS Number 2038-03-1 Molecular Weight 130.188
Density 1.0±0.1 g/cm3 Boiling Point 202.6±20.0 °C at 760 mmHg
Molecular Formula C6H14N2O Melting Point 24 °C
MSDS Chinese USA Flash Point 76.3±21.8 °C
Symbol GHS05 GHS07
GHS05, GHS07
Signal Word Danger

 Names

Name 2-morpholin-4-ylethanamine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 202.6±20.0 °C at 760 mmHg
Melting Point 24 °C
Molecular Formula C6H14N2O
Molecular Weight 130.188
Flash Point 76.3±21.8 °C
Exact Mass 130.110611
PSA 38.49000
LogP -1.01
Vapour Pressure 0.3±0.4 mmHg at 25°C
Index of Refraction 1.474
Water Solubility soluble

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
QD7350000
CHEMICAL NAME :
Morpholine, 4-(2-aminoethyl)-
CAS REGISTRY NUMBER :
2038-03-1
BEILSTEIN REFERENCE NO. :
0104378
LAST UPDATED :
199701
DATA ITEMS CITED :
8
MOLECULAR FORMULA :
C6-H14-N2-O
MOLECULAR WEIGHT :
130.22
WISWESSER LINE NOTATION :
T6N DOTJ A2Z

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Open irritation test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 26,269,1944
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,888,1986
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,888,1986 ** ACUTE TOXICITY DATA **
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
3 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 26,269,1944
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2145 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 109,108,1957
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
300 uL/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 26,269,1944 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X1251 No. of Facilities: 119 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 2625 (estimated) No. of Female Employees: 597 (estimated)

 Safety Information

Symbol GHS05 GHS07
GHS05, GHS07
Signal Word Danger
Hazard Statements H302-H314-H317
Precautionary Statements P280-P305 + P351 + P338-P310
Personal Protective Equipment Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes T:Toxic;C:Corrosive;
Risk Phrases R22;R24;R34;R43
Safety Phrases S26-S36/37/39-S45
RIDADR UN 2735 8/PG 2
WGK Germany 2
RTECS QD7350000
Packaging Group III
Hazard Class 8
HS Code 2934999090

 Synthetic Route

 Customs

HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles12

More Articles
Carbonic anhydrase activators: activation of the human tumor-associated isozymes IX and XII with amino acids and amines.

Bioorg. Med. Chem. 16 , 3530-6, (2008)

The first activation study of the human carbonic anhydrase (hCA, EC 4.2.1.1) isoforms associated to tumors, hCA IX and XII, with a small library of natural and non-natural amino acids as well as aroma...

Carbonic anhydrase activators: activation of isozyme XIII with amino acids and amines.

Bioorg. Med. Chem. Lett. 16 , 3955-9, (2006)

The first activation study of isoform XIII of carbonic anhydrase (CA, EC 4.2.1.1) is reported. A series of amino acids and amines incorporating protonatable moieties of the primary/heterocyclic amine ...

Carbonic anhydrase activators: the first activation study of the human secretory isoform VI with amino acids and amines.

Bioorg. Med. Chem. 15 , 5351-7, (2007)

The secretory isozyme of human carbonic anhydrase (hCA, EC 4.2.1.1), hCA VI, has been cloned, expressed, and purified in a bacterial expression system. The kinetic parameters for the CO(2) hydration r...

 Synonyms

2-morpholinoethan-1-amine
N-2-Aminoethylmorfolin [Czech]
EINECS 218-011-6
N-Aminoethylmorpholine
N-(2-aminoethyl)-morpholine
2-(N-morpholino)ethylamine
2-(morpholin-4-yl)-ethyl amine
MFCD00006182
4-(2-aminoethyl)-morpholine
4-MORPHOLINEETHANAMINE
2-Morpholinoethylamine
2-(Morpholin-4-yl)ethanamin
2-(4-Morpholinyl)ethanamine
4-(2-Aminoethyl)morpholine
2-morpholinoethanamine
Morpholine,4-(2-aminoethyl)
2-(morpholin-4-yl)ethanamine
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