Antitrypanosomal agent 4

Modify Date: 2025-08-24 17:52:53

Antitrypanosomal agent 4 Structure
Antitrypanosomal agent 4 structure
Common Name Antitrypanosomal agent 4
CAS Number 2456427-48-6 Molecular Weight 419.84
Density N/A Boiling Point N/A
Molecular Formula C18H14ClN3O5S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Antitrypanosomal agent 4


Antitrypanosomal agent 4 (compound 19) is a potent and blood-brain barrier permeable antitrypanosomal agent. Antitrypanosomal agent 4 has good activity against Trypanosoma cruzi (T. cruzi) and Trypanosoma brucei brucei (T. b. brucei) with IC50s of 1.2 μM and 70 nM, respectively[1].

 Names

Name Antitrypanosomal agent 4

 Antitrypanosomal agent 4 Biological Activity

Description Antitrypanosomal agent 4 (compound 19) is a potent and blood-brain barrier permeable antitrypanosomal agent. Antitrypanosomal agent 4 has good activity against Trypanosoma cruzi (T. cruzi) and Trypanosoma brucei brucei (T. b. brucei) with IC50s of 1.2 μM and 70 nM, respectively[1].
Related Catalog
Target

IC50: 1.2 μM (T. cruzi), 70 nM (T. b. brucei)[1]

References

[1]. Fersing C, Boudot C, Castera-Ducros C, et al. 8-Alkynyl-3-nitroimidazopyridines display potent antitrypanosomal activity against both T. b. brucei and cruzi. Eur J Med Chem. 2020;202:112558.

 Chemical & Physical Properties

Molecular Formula C18H14ClN3O5S
Molecular Weight 419.84
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.