Antitrypanosomal agent 7
Modify Date: 2024-04-05 22:38:58
Antitrypanosomal agent 7 structure
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Common Name | Antitrypanosomal agent 7 | ||
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| CAS Number | 2492436-38-9 | Molecular Weight | 480.43 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C23H31Cl2N5O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Antitrypanosomal agent 7Antitrypanosomal agent 7 (compound 18c) is a potent and antitrypanosomal agent with favorable ADME properties. Antitrypanosomal agent 7 is > 2-fold more potent against Trypanosoma brucei (T. brucei) than Nifurtimox, with an IC50 value of 0.71 μM. Antitrypanosomal agent 7 has strong interaction to DNA and can bind with high selectivity to AT-rich DNA[1]. |
| Name | Antitrypanosomal agent 7 |
|---|
| Description | Antitrypanosomal agent 7 (compound 18c) is a potent and antitrypanosomal agent with favorable ADME properties. Antitrypanosomal agent 7 is > 2-fold more potent against Trypanosoma brucei (T. brucei) than Nifurtimox, with an IC50 value of 0.71 μM. Antitrypanosomal agent 7 has strong interaction to DNA and can bind with high selectivity to AT-rich DNA[1]. |
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| Related Catalog | |
| Target |
IC50: 0.71 μM (T. brucei)[1] |
| References |
| Molecular Formula | C23H31Cl2N5O2 |
|---|---|
| Molecular Weight | 480.43 |